The 90-day prognostic value of copeptin in acute intracerebral hemorrhage

The aim of the study was to assess the 90-day prognostic value of copeptin in a group of Chinese patients with acute intracerebral hemorrhage (ICH). In this study, all consecutive patients with first-ever ICH from 2010 to 2012 were recruited to participate in the study. On admission, plasma copeptin...

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Bibliographic Details
Published in:Neurological sciences 2014-11, Vol.35 (11), p.1673-1679
Main Authors: Wei, Zhi-Jun, Ou, Yang-Qi, Li, Xue, Li, Hua
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Area Under Curve
Biomarkers - blood
Enzyme-Linked Immunosorbent Assay
Female
Glycopeptides - blood
Humans
Intracranial Hemorrhages - blood
Male
Medicine
Medicine & Public Health
Middle Aged
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Original Article
Prognosis
Psychiatry
Recovery of Function - physiology
ROC Curve
Sensitivity and Specificity
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Summary:The aim of the study was to assess the 90-day prognostic value of copeptin in a group of Chinese patients with acute intracerebral hemorrhage (ICH). In this study, all consecutive patients with first-ever ICH from 2010 to 2012 were recruited to participate in the study. On admission, plasma copeptin levels were measured by enzyme-linked immunosorbent assay. The Glasgow Coma Scale (GCS) and Hemphill ICH scores were assessed on admission blinded to plasma copeptin levels. For the assessment of functional outcome at 90 days, Modified Rankin Scale was used. During the study period, 271 patients were diagnosed as ICH and were included in the analysis. The median GCS score on admission was 11 points. Patients with an unfavorable outcomes and non-survivors had significantly increased plasma copeptin levels on admission ( P  
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-014-1809-2