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Pharmacokinetic interactions between ethanol and heroin: A study on post-mortem cases
Highlights • Analysis of autopsy samples revealed ethanol interference with heroin metabolism. • Both the metabolism of 6-monoacetylmorphine and morphine were inhibited. • The same findings were observed in cases involving a very recent intake of heroin.
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| Published in: | Forensic science international 2014-09, Vol.242, p.127-134 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c513t-e1da1e1148ab3d454cba09c3e1e7aa650f97d59e543fa69478d0db98eb9d2c4d3 |
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| cites | cdi_FETCH-LOGICAL-c513t-e1da1e1148ab3d454cba09c3e1e7aa650f97d59e543fa69478d0db98eb9d2c4d3 |
| container_end_page | 134 |
| container_issue | |
| container_start_page | 127 |
| container_title | Forensic science international |
| container_volume | 242 |
| creator | Thaulow, C.H Høiseth, G Andersen, J.M Handal, M Mørland, J |
| description | Highlights • Analysis of autopsy samples revealed ethanol interference with heroin metabolism. • Both the metabolism of 6-monoacetylmorphine and morphine were inhibited. • The same findings were observed in cases involving a very recent intake of heroin. |
| doi_str_mv | 10.1016/j.forsciint.2014.06.032 |
| format | article |
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| fulltext | fulltext |
| identifier | ISSN: 0379-0738 |
| ispartof | Forensic science international, 2014-09, Vol.242, p.127-134 |
| issn | 0379-0738 1872-6283 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1629342670 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Autopsies Blood Central Nervous System Depressants - blood Central Nervous System Depressants - pharmacokinetics Drug Interactions Ethanol Ethanol - blood Ethanol - pharmacokinetics Ethyl alcohol Forensic sciences Forensic Toxicology Heroin Heroin - analysis Heroin - pharmacokinetics Humans Intakes Metabolism Metabolites Morphine Morphine Derivatives - analysis Narcotics Narcotics - analysis Narcotics - pharmacokinetics Pathology Pharmacokinetic interactions Post-mortem Studies Subgroups Urine |
| title | Pharmacokinetic interactions between ethanol and heroin: A study on post-mortem cases |
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