Differences in CT features of peritoneal carcinomatosis, sarcomatosis, and lymphomatosis: Retrospective analysis of 122 cases at a tertiary cancer institution

Aims To study the differences in the imaging features of spread from the three cancer cell lines, namely epithelial, sarcomatoid, and lymphoid, resulting in peritoneal carcinomatosis, peritoneal sarcomatosis, and peritoneal lymphomatosis, respectively. Materials and methods In this institutional rev...

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Bibliographic Details
Published in:Clinical radiology 2014-12, Vol.69 (12), p.1219-1227
Main Authors: O'Neill, A.C, Shinagare, A.B, Rosenthal, M.H, Tirumani, S.H, Jagannathan, J.P, Ramaiya, N.H
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Carcinoma - diagnostic imaging
Diagnosis, Differential
Female
Humans
Image Processing, Computer-Assisted - methods
Lymphoma - diagnostic imaging
Male
Middle Aged
Peritoneal Neoplasms - diagnostic imaging
Peritoneum - diagnostic imaging
Radiology
Retrospective Studies
Sarcoma - diagnostic imaging
Tertiary Care Centers
Tomography, X-Ray Computed - methods
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Summary:Aims To study the differences in the imaging features of spread from the three cancer cell lines, namely epithelial, sarcomatoid, and lymphoid, resulting in peritoneal carcinomatosis, peritoneal sarcomatosis, and peritoneal lymphomatosis, respectively. Materials and methods In this institutional review board-approved Health Insurance Portability and Accountability Act (HIPAA)-compliant retrospective study, an electronic radiology database was searched to identify patients with peritoneal tumour spread who underwent CT imaging at Dana-Farber Cancer Institute, a tertiary cancer institution, between January 2011 and December 2012. Out of 1214 patients with possible peritoneal tumour spread on the radiology reports, 122 patients were included with histopathologically confirmed peritoneal disease (50 randomly selected patients with peritoneal carcinomatosis and sarcomatosis each, and all 22 patients with lymphomatosis). Two blinded, fellowship-trained radiologists in consensus reviewed the CT images in random order and recorded the imaging findings of peritoneal tumour spread. The statistical analysis was performed in two steps: the first comparing incidence of various features in each group and the second step was a pairwise analysis between each cohort. Results Peritoneal carcinomatosis more frequently had ascites, peritoneal thickening, and omental cake (all p  ≤ 0.001). Measurable nodules were less common in peritoneal carcinomatosis ( p  
ISSN:0009-9260
1365-229X
DOI:10.1016/j.crad.2014.06.019