The effect of a bioglass paste on enamel exposed to erosive challenge

• Published in: Journal of dentistry 2014-11, Vol.42 (11), p.1458-1463
• Main Authors: Bakry, Ahmed Samir, Marghalani, Hanadi Y, Amin, Omayma A, Tagami, Junji
• Format: Article
• Language: English
• Subjects: 45S5 bioglass; Acids; Beverages - adverse effects; Cariostatic Agents - therapeutic use; Ceramics - chemistry; Citrus sinensis; Crystallography; Dental Enamel - chemistry; Dental Enamel - drug effects; Dental Enamel - ultrastructure; Dentistry; Electron Probe Microanalysis; Enamel; Erosion; Fluorides; Fluorides, Topical - therapeutic use; Fruit; Fruit juices; Glass - chemistry; Hardness; Humans; Hydrogen-Ion Concentration; Materials Testing; Mechanical properties; Micro-indentation; Microscopy, Electron, Scanning; Random Allocation; Remineralization; Resin Cements - chemistry; Spectrometry, X-Ray Emission; Tooth Erosion - pathology; Tooth Erosion - prevention & control; Tooth Remineralization - methods
• ISSN: 0300-5712; 1879-176X
• DOI: 10.1016/j.jdent.2014.05.014

Abstract Objectives The current study is evaluating the effect of using a 45S5 bioglass paste and topical fluoride application on the cross sectional micro-hardness and the chemical surface changes of eroded enamel. Methods Enamel discs were obtained from the buccal surface of one hundred extracted human non-carious third molars. The enamel surfaces were ground flat and each disc was coated with two layers of acid resistant nail varnish except for an exposed treatment window (3 mm × 2 mm) on the buccal surface of the tooth. All specimens were challenged for 60 min by orange juice (Tropicana, Chicago, USA) pH 3.85 + 0.5. The specimens were divided into four groups: the 45S5 bioglass paste group, fluoride gel group (5 min application), fluoride gel group (24 h application) while the rest of specimens served as control. The cross-sectional micro-hardness of 20 specimens from each group was measured. Five specimens from each group had their top eroded enamel surfaces examined by SEM-EDS. One-way ANOVA was used to compare the cross-sectional micro-hardness of the three groups p < 0.05. Results 45S5 bioglass paste application significantly improved the sub-surface eroded enamel when compared to fluoride and control specimens ( p < 0.05). Conclusion 45S5 bioglass paste can efficiently improve the micro-hardness of the sub-surface eroded enamel surface. Clinical significance The use of the 45S5 Bioglass paste can be used efficiently as a potent remineralizing agent for the sub-surface enamel lesions resulting from erosive challenges.