No Additional Benefit With Use of a Fibrin Sealant to Decrease Peri-Operative Blood Loss During Primary Total Knee Arthroplasty

Abstract Blood loss remains a substantial problem associated TKA. This study evaluated the efficacy of a fibrin sealant on: (1) blood loss; (2) blood transfusions; and (3) length of stay. We evaluated the records of 113 consecutive patients with sealant and 70 without sealant. There was no significa...

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Bibliographic Details
Published in:The Journal of arthroplasty 2014-11, Vol.29 (11), p.2109-2112
Main Authors: Maheshwari, Aditya V., MD, Korshunov, Yevgeiny, MD, Naziri, Qais, MD, Pivec, Robert, MD, Mont, Michael A., MD, Rasquinha, Vijay J., MD
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Arthroplasty, Replacement, Knee
Blood Loss, Surgical - prevention & control
Blood Transfusion
Female
fibrin sealant
Fibrin Tissue Adhesive - therapeutic use
Hematocrit
Hemoglobins - analysis
hemostasis
Hemostatics - therapeutic use
Humans
Length of Stay
Male
Middle Aged
Orthopedics
Postoperative Hemorrhage - prevention & control
Retrospective Studies
total knee
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Summary:Abstract Blood loss remains a substantial problem associated TKA. This study evaluated the efficacy of a fibrin sealant on: (1) blood loss; (2) blood transfusions; and (3) length of stay. We evaluated the records of 113 consecutive patients with sealant and 70 without sealant. There was no significant difference in the hemoglobin levels (all 9.5–10 g/dL) on each of three postoperative days. There was also no significant difference in the intraoperative blood loss, postoperative blood loss or the total perioperative blood loss in both groups. The mean requirement in each patient was 2.5 ± 2.4 units in the fibrin sealant group compared to 2.0 ± 0.8 units in the non-fibrin sealant group. We have stopped using fibrin sealant based on this study.
ISSN:0883-5403
1532-8406
DOI:10.1016/j.arth.2014.02.034