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No Additional Benefit With Use of a Fibrin Sealant to Decrease Peri-Operative Blood Loss During Primary Total Knee Arthroplasty

Abstract Blood loss remains a substantial problem associated TKA. This study evaluated the efficacy of a fibrin sealant on: (1) blood loss; (2) blood transfusions; and (3) length of stay. We evaluated the records of 113 consecutive patients with sealant and 70 without sealant. There was no significa...

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Published in:	The Journal of arthroplasty 2014-11, Vol.29 (11), p.2109-2112
Main Authors:	Maheshwari, Aditya V., MD, Korshunov, Yevgeiny, MD, Naziri, Qais, MD, Pivec, Robert, MD, Mont, Michael A., MD, Rasquinha, Vijay J., MD
Format:	Article
Language:	English
Subjects:	Adult Aged Aged, 80 and over Arthroplasty, Replacement, Knee Blood Loss, Surgical - prevention & control Blood Transfusion Female fibrin sealant Fibrin Tissue Adhesive - therapeutic use Hematocrit Hemoglobins - analysis hemostasis Hemostatics - therapeutic use Humans Length of Stay Male Middle Aged Orthopedics Postoperative Hemorrhage - prevention & control Retrospective Studies total knee
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container_title	The Journal of arthroplasty
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creator	Maheshwari, Aditya V., MD Korshunov, Yevgeiny, MD Naziri, Qais, MD Pivec, Robert, MD Mont, Michael A., MD Rasquinha, Vijay J., MD
description	Abstract Blood loss remains a substantial problem associated TKA. This study evaluated the efficacy of a fibrin sealant on: (1) blood loss; (2) blood transfusions; and (3) length of stay. We evaluated the records of 113 consecutive patients with sealant and 70 without sealant. There was no significant difference in the hemoglobin levels (all 9.5–10 g/dL) on each of three postoperative days. There was also no significant difference in the intraoperative blood loss, postoperative blood loss or the total perioperative blood loss in both groups. The mean requirement in each patient was 2.5 ± 2.4 units in the fibrin sealant group compared to 2.0 ± 0.8 units in the non-fibrin sealant group. We have stopped using fibrin sealant based on this study.
doi_str_mv	10.1016/j.arth.2014.02.034
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This study evaluated the efficacy of a fibrin sealant on: (1) blood loss; (2) blood transfusions; and (3) length of stay. We evaluated the records of 113 consecutive patients with sealant and 70 without sealant. There was no significant difference in the hemoglobin levels (all 9.5–10 g/dL) on each of three postoperative days. There was also no significant difference in the intraoperative blood loss, postoperative blood loss or the total perioperative blood loss in both groups. The mean requirement in each patient was 2.5 ± 2.4 units in the fibrin sealant group compared to 2.0 ± 0.8 units in the non-fibrin sealant group. 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subjects	Adult Aged Aged, 80 and over Arthroplasty, Replacement, Knee Blood Loss, Surgical - prevention & control Blood Transfusion Female fibrin sealant Fibrin Tissue Adhesive - therapeutic use Hematocrit Hemoglobins - analysis hemostasis Hemostatics - therapeutic use Humans Length of Stay Male Middle Aged Orthopedics Postoperative Hemorrhage - prevention & control Retrospective Studies total knee
title	No Additional Benefit With Use of a Fibrin Sealant to Decrease Peri-Operative Blood Loss During Primary Total Knee Arthroplasty
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