Primary intermediate-grade cardiac myxofibrosarcoma with osseous metaplasia: an extremely rare occurrence with a previously unreported feature

Abstract Primary cardiac myxofibrosarcoma (MFS) is a very rare cardiac tumor with no more than 22 cases reported in the literature, including our case. We report an MFS arising in the left atrium in a 65-year-old woman who presented with pneumonia and cardiac failure. The 9.5-cm mass was diagnosed b...

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Bibliographic Details
Published in:Cardiovascular pathology 2014-11, Vol.23 (6), p.376-378
Main Authors: Sanchez-Uribe, Magdalena, Retamero, Juan Antonio, Gomez Leon, J, Montoya Perez, Jorge, Quiñonez, Enoe
Format: Article
Language:English
Subjects:
Aged
Atrium
Diagnosis, Differential
Echocardiography
Female
Fibrosarcoma - diagnostic imaging
Fibrosarcoma - pathology
Heart Atria - pathology
Heart Neoplasms - diagnostic imaging
Heart Neoplasms - pathology
Humans
Intermediate-grade
Metaplasia
Mitral Valve Insufficiency - diagnostic imaging
Myxofibrosarcoma
Osseous metaplasia
Osteoclasts - pathology
Pathology
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Summary:Abstract Primary cardiac myxofibrosarcoma (MFS) is a very rare cardiac tumor with no more than 22 cases reported in the literature, including our case. We report an MFS arising in the left atrium in a 65-year-old woman who presented with pneumonia and cardiac failure. The 9.5-cm mass was diagnosed by echocardiogram. Histopathology examination showed an intermediate-grade MFS with osseous metaplasia, a feature that has not been reported before.
ISSN:1054-8807
1879-1336
DOI:10.1016/j.carpath.2014.07.006