Angiosarcoma arising from the frontal sinus

Abstract Primary sinonasal angiosarcomas are very rare tumors. They typically occur in the nasal cavity of middle-aged patients. They are classically highly aggressive. Primary treatment is surgical excision when feasible. We describe a unique case of angiosarcoma in a young woman arising from the f...

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Bibliographic Details
Published in:American journal of otolaryngology 2014-11, Vol.35 (6), p.806-809
Main Authors: Tomovic, Senja, MD, Kalyoussef, Evelyne, MD, Mirani, Neena M., MD, Baredes, Soly, MD, FACS, Eloy, Jean Anderson, MD, FACS
Format: Article
Language:English
Subjects:
Adult
Biopsy
Chemotherapy
English literature
Ethmoid Sinus - pathology
Female
Frontal Sinus - diagnostic imaging
Frontal Sinus - pathology
Hemangiosarcoma - diagnostic imaging
Hemangiosarcoma - pathology
Hemangiosarcoma - therapy
Humans
Magnetic Resonance Imaging
Medical imaging
Medical prognosis
Metastasis
NMR
Nuclear magnetic resonance
Otolaryngology
Paranasal Sinus Neoplasms - diagnostic imaging
Paranasal Sinus Neoplasms - pathology
Paranasal Sinus Neoplasms - therapy
Positron-Emission Tomography
Sinuses
Surgery
Tomography
Tomography, X-Ray Computed
Tumors
Vascular endothelial growth factor
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Description
Summary:Abstract Primary sinonasal angiosarcomas are very rare tumors. They typically occur in the nasal cavity of middle-aged patients. They are classically highly aggressive. Primary treatment is surgical excision when feasible. We describe a unique case of angiosarcoma in a young woman arising from the frontal sinus with distant metastasis. This case represents the first report of angiosarcoma arising from the frontal sinus in the English literature. The traditional treatment options for the advanced nature of her disease and overall poor prognosis are discussed. We further review the literature and discuss alternative treatments options. Newer chemotherapeutic regiments on the horizon show promise in helping to control this disease.
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2014.08.003