Short report: Predictors of severe disease in melioidosis patients in Kuala Lumpur, Malaysia

The predictors of severe disease or death were determined for 85 melioidosis patients in Kuala Lumpur, Malaysia. Most of the patients were male, > 40 years old, and diabetic. Severe disease or death occurred in 28 (32.9%) cases. Lower lymphocyte counts and positive blood cultures were significant...

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Bibliographic Details
Published in:The American journal of tropical medicine and hygiene 2014-12, Vol.91 (6), p.1176-1178
Main Authors: Mohd Roslani, Ardita Dewi Roslani, Tay, Sun Tee, Puthucheary, Savithri D, Rukumani, Devi V, Sam, I-Ching
Format: Article
Language:English
Subjects:
Adult
Female
Humans
Malaysia - epidemiology
Male
Melioidosis - physiopathology
Severity of Illness Index
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Summary:The predictors of severe disease or death were determined for 85 melioidosis patients in Kuala Lumpur, Malaysia. Most of the patients were male, > 40 years old, and diabetic. Severe disease or death occurred in 28 (32.9%) cases. Lower lymphocyte counts and positive blood cultures were significant independent predictors of severe disease, but age, presentations with pneumonia, inappropriate empirical antibiotics, or flagellin types of the infecting isolates were not. Knowledge of local predictors of severe disease is useful for clinical management.
ISSN:1476-1645
DOI:10.4269/ajtmh.14-0354