Research Article: Clinical Characteristics of Isolated Anterior Cerebral Artery Territory Infarction Due to Arterial Dissection

• Published in: Journal of stroke and cerebrovascular diseases 2014-11, Vol.23 (10), p.2907-2913
• Main Authors: Nagamine, Yuito, MD, Fukuoka, Takuya, MD, Hayashi, Takeshi, MD, Kato, Yuji, MD, Deguchi, Ichiro, MD, Maruyama, Hajime, MD, Horiuchi, Yohsuke, MD, Sano, Hiroyasu, MD, Mizuno, Satoko, MD, Tanahashi, Norio, MD
• Format: Article
• Language: English
• Subjects: Adult; Age Factors; Aged; Aged, 80 and over; Aneurysm, Dissecting - complications; Aneurysm, Dissecting - diagnosis; Aneurysm, Dissecting - therapy; Angiography, Digital Subtraction; anterior cerebral artery; Cardiovascular; Cerebral Angiography - methods; Cerebral infarction; dissection; Female; Headache - etiology; Humans; Infarction, Anterior Cerebral Artery - diagnosis; Infarction, Anterior Cerebral Artery - etiology; Infarction, Anterior Cerebral Artery - therapy; Intracranial Aneurysm - complications; Intracranial Aneurysm - diagnosis; Intracranial Aneurysm - therapy; Japan; Magnetic Resonance Angiography; magnetic resonance cisternography; Male; Middle Aged; Neurology; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Tomography, X-Ray Computed
• ISSN: 1052-3057; 1532-8511
• DOI: 10.1016/j.jstrokecerebrovasdis.2014.07.017

Background Isolated brain infarction in the anterior cerebral artery (ACA) territory is rare, and its etiology has not yet been fully elucidated. Thus, we aimed to determine the etiologic and clinical characteristics of patients with isolated ACA territory infarction due to arterial dissection. Methods Of 2315 patients with acute cerebral infarction admitted to our hospital between April 2007 and September 2013, 34 patients (1.5%; 28 men, 6 women; mean age, 65 ± 15 years) suffered isolated ACA territory infarction. We performed cranial magnetic resonance (MR) imaging and MR angiography for all the patients. Whenever possible, we also performed 3-dimensional computed tomography angiography, digital subtraction angiography, and MR cisternography to diagnose the stroke subtype. Results The stroke subtypes of the 34 patients with isolated ACA territory infarction were atherothrombotic infarction, cardioembolic infarction, arterial dissection, and unclassified in 11 patients (32%), 11 patients (32%), 11 patients (32%), and 1 patient (3%), respectively. The mean ages at onset were 48 ± 9 and 72 ± 11 years in the dissection and nondissection groups, respectively ( P