Advances in the treatment of secondary osteoporosis

Osteoporosis is being increasingly recognised in paediatric practice as a consequence of the increasing life expectancy of children who suffer from chronic diseases and other factors. There are many non-pharmacological measures that can improve children' bone health, for example, avoiding infla...

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Bibliographic Details
Published in:Anales de pediatría (Barcelona, Spain : 2003) Spain : 2003), 2014-12, Vol.81 (6), p.399.e1-399.e7
Main Authors: Galindo Zavala, R, Núñez Cuadros, E, Díaz Cordovés-Rego, G, Urda Cardona, A L
Format: Article
Language:Spanish
Subjects:
Adult
Child
Dietary Supplements
Diphosphonates - therapeutic use
Humans
Osteoporosis - etiology
Osteoporosis - therapy
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Summary:Osteoporosis is being increasingly recognised in paediatric practice as a consequence of the increasing life expectancy of children who suffer from chronic diseases and other factors. There are many non-pharmacological measures that can improve children' bone health, for example, avoiding inflammatory activity and osteotoxic treatments; increasing sun exposure and weight-bearing exercise, and maintaining an adequate nutritional status. Vitamin D and calcium supplements have been proposed as a measure to increase bone mass, but their effect and therapeutic indications are not completely clear. On the other hand, bisphosphonates are currently the only pharmacological alternative for the patients with infantile secondary osteoporosis. However, more studies are required on the therapeutic indications, posology, and long term secondary effects of biphosphonates. The aim of this article is to analyze the scientific evidence of the effectiveness of the therapeutic alternatives for childhood secondary osteoporosis and their safety in children.
ISSN:1695-9531
DOI:10.1016/j.anpedi.2014.05.003