Health related quality of life in people with advanced chronic liver disease

Summary Cirrhosis has a long natural history with considerable symptomatic impacts, particularly in advancing disease. Measuring health related quality of life (HRQOL) in liver disease provides detail about the nature and extent of its effects on individuals. Understanding the drivers of impaired HR...

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Bibliographic Details
Published in:Journal of hepatology 2014-11, Vol.61 (5), p.1158-1165
Main Authors: Orr, James G, Homer, Tara, Ternent, Laura, Newton, Julia, McNeil, Calum J, Hudson, Mark, Jones, David E.J
Format: Article
Language:English
Subjects:
Ascites
Chronic Disease
Cirrhosis
Gastroenterology and Hepatology
Health related quality of life
Hepatic Encephalopathy
Humans
Liver
Liver Cirrhosis
Liver Diseases - etiology
Quality of Life
Severity of Illness Index
Surveys and Questionnaires
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Summary:Summary Cirrhosis has a long natural history with considerable symptomatic impacts, particularly in advancing disease. Measuring health related quality of life (HRQOL) in liver disease provides detail about the nature and extent of its effects on individuals. Understanding the drivers of impaired HRQOL can help identify targets for improvement through new treatments or health systems service delivery. Evaluation of novel therapies which target symptomatic improvement, should be done with suitable outcome measures, including HRQOL assessment. In this article, we provide an overview of HRQOL in advanced liver disease for the clinician. A clear description of the important HRQOL tools is given alongside a discussion of the factors, which are known to contribute to impaired HRQOL in advanced liver disease.
ISSN:0168-8278
1600-0641
DOI:10.1016/j.jhep.2014.06.034