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Health related quality of life in people with advanced chronic liver disease
Summary Cirrhosis has a long natural history with considerable symptomatic impacts, particularly in advancing disease. Measuring health related quality of life (HRQOL) in liver disease provides detail about the nature and extent of its effects on individuals. Understanding the drivers of impaired HR...
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Published in: | Journal of hepatology 2014-11, Vol.61 (5), p.1158-1165 |
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container_title | Journal of hepatology |
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creator | Orr, James G Homer, Tara Ternent, Laura Newton, Julia McNeil, Calum J Hudson, Mark Jones, David E.J |
description | Summary Cirrhosis has a long natural history with considerable symptomatic impacts, particularly in advancing disease. Measuring health related quality of life (HRQOL) in liver disease provides detail about the nature and extent of its effects on individuals. Understanding the drivers of impaired HRQOL can help identify targets for improvement through new treatments or health systems service delivery. Evaluation of novel therapies which target symptomatic improvement, should be done with suitable outcome measures, including HRQOL assessment. In this article, we provide an overview of HRQOL in advanced liver disease for the clinician. A clear description of the important HRQOL tools is given alongside a discussion of the factors, which are known to contribute to impaired HRQOL in advanced liver disease. |
doi_str_mv | 10.1016/j.jhep.2014.06.034 |
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Measuring health related quality of life (HRQOL) in liver disease provides detail about the nature and extent of its effects on individuals. Understanding the drivers of impaired HRQOL can help identify targets for improvement through new treatments or health systems service delivery. Evaluation of novel therapies which target symptomatic improvement, should be done with suitable outcome measures, including HRQOL assessment. In this article, we provide an overview of HRQOL in advanced liver disease for the clinician. 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A clear description of the important HRQOL tools is given alongside a discussion of the factors, which are known to contribute to impaired HRQOL in advanced liver disease.</description><subject>Ascites</subject><subject>Chronic Disease</subject><subject>Cirrhosis</subject><subject>Gastroenterology and Hepatology</subject><subject>Health related quality of life</subject><subject>Hepatic Encephalopathy</subject><subject>Humans</subject><subject>Liver</subject><subject>Liver Cirrhosis</subject><subject>Liver Diseases - etiology</subject><subject>Quality of Life</subject><subject>Severity of Illness Index</subject><subject>Surveys and Questionnaires</subject><issn>0168-8278</issn><issn>1600-0641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNp9kUtr3DAUhUVpaSZp_0AXwcts7FxZrxkohRKaBwx00XYtZOmakaOxHcmeMP--MpNmkUVXd_OdA-e7hHyhUFGg8rqruh2OVQ2UVyArYPwdWVEJUILk9D1ZZWhdrmu1PiPnKXUAwGDDP5KzWgCFWmxWZHuPJky7ImIwE7riaTbBT8diaIvgWyx8X4w4jAGLZ58x4w6mt5mzuzj03mbogLFwPqFJ-Il8aE1I-PnlXpA_tz9-39yX2593Dzfft6UVtZhKp4RTDh0qaKkCbkRjOaMbK8GJhhvaSGGhgUbQVjDVSMYYl9KJlq6VAMkuyNWpd4zD04xp0nufLIZgehzmpKlkXOXZQmW0PqE2DilFbPUY_d7Eo6agF4u604tFvVjUIHW2mEOXL_1zs0f3GvmnLQNfTwDmlQePUSfrcRHjI9pJu8H_v__bm7gNPts04RGPmLphjn32p6lOtQb9a_nj8kbKAbjknP0FXNeXIQ</recordid><startdate>20141101</startdate><enddate>20141101</enddate><creator>Orr, James G</creator><creator>Homer, Tara</creator><creator>Ternent, Laura</creator><creator>Newton, Julia</creator><creator>McNeil, Calum J</creator><creator>Hudson, Mark</creator><creator>Jones, David E.J</creator><general>Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141101</creationdate><title>Health related quality of life in people with advanced chronic liver disease</title><author>Orr, James G ; Homer, Tara ; Ternent, Laura ; Newton, Julia ; McNeil, Calum J ; Hudson, Mark ; Jones, David E.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-d75d7dede70f1704a5bc4319c60d5b4a1b65c0b0b51f537b6333466d5f1875063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Ascites</topic><topic>Chronic Disease</topic><topic>Cirrhosis</topic><topic>Gastroenterology and Hepatology</topic><topic>Health related quality of life</topic><topic>Hepatic Encephalopathy</topic><topic>Humans</topic><topic>Liver</topic><topic>Liver Cirrhosis</topic><topic>Liver Diseases - etiology</topic><topic>Quality of Life</topic><topic>Severity of Illness Index</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Orr, James G</creatorcontrib><creatorcontrib>Homer, Tara</creatorcontrib><creatorcontrib>Ternent, Laura</creatorcontrib><creatorcontrib>Newton, Julia</creatorcontrib><creatorcontrib>McNeil, Calum J</creatorcontrib><creatorcontrib>Hudson, Mark</creatorcontrib><creatorcontrib>Jones, David E.J</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Orr, James G</au><au>Homer, Tara</au><au>Ternent, Laura</au><au>Newton, Julia</au><au>McNeil, Calum J</au><au>Hudson, Mark</au><au>Jones, David E.J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Health related quality of life in people with advanced chronic liver disease</atitle><jtitle>Journal of hepatology</jtitle><addtitle>J Hepatol</addtitle><date>2014-11-01</date><risdate>2014</risdate><volume>61</volume><issue>5</issue><spage>1158</spage><epage>1165</epage><pages>1158-1165</pages><issn>0168-8278</issn><eissn>1600-0641</eissn><abstract>Summary Cirrhosis has a long natural history with considerable symptomatic impacts, particularly in advancing disease. 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subjects | Ascites Chronic Disease Cirrhosis Gastroenterology and Hepatology Health related quality of life Hepatic Encephalopathy Humans Liver Liver Cirrhosis Liver Diseases - etiology Quality of Life Severity of Illness Index Surveys and Questionnaires |
title | Health related quality of life in people with advanced chronic liver disease |
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