Planar waveguide immunosensor with fluorescent liposome amplification

A regenerable planar waveguide immunosensor for theophylline has been developed. The use of theophylline-labeled liposomes provides one order of magnitude greater signal enhancement over theophylline derivatized with fluorescein.

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Bibliographic Details
Published in:Analytical chemistry (Washington) 1992-01, Vol.64 (1), p.55-60
Main Authors: Choquette, Steven J, Locascio-Brown, Laurie, Durst, Richard A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biotechnology
Chemistry
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Others
Sensors
Various methods and equipments
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Description
Summary:A regenerable planar waveguide immunosensor for theophylline has been developed. The use of theophylline-labeled liposomes provides one order of magnitude greater signal enhancement over theophylline derivatized with fluorescein.
ISSN:0003-2700
1520-6882
DOI:10.1021/ac00025a011