Relative impact of earlier diagnosis and improved treatment on survival for colorectal cancer: A US database study among elderly patients

Highlights • Improvements in screening were associated with migration of cancer toward earlier stage. • Improvements in screening and chemotherapy were translated into real world effectiveness. • Changes toward earlier tumor stage and smaller size contributed to 20% of survival increase. • Survival...

Full description

Saved in:
Bibliographic Details
Published in:Cancer epidemiology 2014-12, Vol.38 (6), p.733-740
Main Authors: Tong, Liyue, Ahn, Chul, Symanski, Elaine, Lai, Dejian, Du, Xianglin L
Format: Article
Language:English
Subjects:
Analysis. Health state
Biological and medical sciences
Cancer
Cancer therapies
Chemotherapy
Colorectal cancer
Epidemiology
Gastroenterology. Liver. Pancreas. Abdomen
General aspects
Health maintenance organizations
Hematology, Oncology and Palliative Medicine
HMOs
Internal Medicine
Medical diagnosis
Medical sciences
Medicare
Migration
Population
Public health. Hygiene
Public health. Hygiene-occupational medicine
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Survival
Tumor stage and size migration
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Improvements in screening were associated with migration of cancer toward earlier stage. • Improvements in screening and chemotherapy were translated into real world effectiveness. • Changes toward earlier tumor stage and smaller size contributed to 20% of survival increase. • Survival increase was largely explained by improvements in chemotherapy (≥71.6%). • Other treatment-related factors also contributed to survival increase (25%).
ISSN:1877-7821
1877-783X
DOI:10.1016/j.canep.2014.10.004