Platelet-activating factor- and thrombin-induced stimulation of p34 super(cdc2)- cyclin histone H1 kinase activity in platelets

Numerous studies of cell cycle control in dividing cells have pointed to the central role of a 34-kDa histone H1 kinase (p34 super(cdc2)) complexed with regulatory subunits known as cyclins. We now report that p34 super(cdc2)-cyclin may also participate in signal transduction in nonproliferating, te...

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Bibliographic Details
Published in:The Journal of biological chemistry 1991-01, Vol.266 (23), p.14889-14892
Main Authors: Samiei, M, Daya-Makin, M, Clark-Lewis, I, Pelech, S L
Format: Article
Language:English
Subjects:
platelet-activating factor
platelets
protamine kinase
sheep
stimulation
thrombin
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Summary:Numerous studies of cell cycle control in dividing cells have pointed to the central role of a 34-kDa histone H1 kinase (p34 super(cdc2)) complexed with regulatory subunits known as cyclins. We now report that p34 super(cdc2)-cyclin may also participate in signal transduction in nonproliferating, terminally differentiated cells.
ISSN:0021-9258