Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca super(2+), guanosine 5'-( gamma -thio)triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin

The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.

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Bibliographic Details
Published in:Biochemical journal 1992-01, Vol.283 (3), p.899-904
Main Authors: Stecher, B, Ahnert-Hilger, G, Weller, U, Kemmer, T P, Gratzl, M
Format: Article
Language:English
Subjects:
acinar cells
amylase
calcium
Clostridium botulinum
Clostridium tetani
cyclic AMP
effects on
GTP
pancreas
rats
release
toxins
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Description
Summary:The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.
ISSN:0264-6021