Can mean platelet volume predict the prognosis of patients with acute kidney injury requiring continuous renal replacement therapy? Response to comments

[...]we tried to show whether MPV has an additional significant prognostic effect on the 28-day all-cause mortality in the patients with AKI treated with CRRT, and we found that increased MPV at CRRT initiation time was significantly associated with higher 28-day all-cause mortality in AKI patients...

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Bibliographic Details
Published in:Journal of critical care 2015-02, Vol.30 (1), p.208-208
Main Authors: Park, Kyoung Sook, MD, Oh, Hyung Jung, MD
Format: Article
Language:English
Subjects:
Acute Kidney Injury - mortality
Acute Kidney Injury - therapy
Confidence intervals
Critical Care
Disease
Drug therapy
Female
Heart attacks
Humans
Male
Mean Platelet Volume
Mortality
Multivariate analysis
Older people
Renal Replacement Therapy - methods
Studies
Citations: Items that this one cites
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Summary:[...]we tried to show whether MPV has an additional significant prognostic effect on the 28-day all-cause mortality in the patients with AKI treated with CRRT, and we found that increased MPV at CRRT initiation time was significantly associated with higher 28-day all-cause mortality in AKI patients treated with CRRT, even after adjustment for platelet count, Acute Physiology and Chronic Health Evaluation (APACHE) II score, cause of AKI, and presence of malignancy. In the present study, we just investigated comorbid diseases as follows: diabetic mellitus, 116 (33.2%); ischemic heart disease, 46 (13.2%); cerebrovascular disease, 32 (9.2%); and connective tissue disease, 7 (2.0%). [...]we demonstrated the impact of MPV on 28-day all-cause mortality even after adjustment for age Charlson Comorbidity Index.
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2014.09.023