Clinical impact of lung age on postoperative readmission in non–small cell lung cancer

• Published in: The Journal of surgical research 2015, Vol.193 (1), p.442-448
• Main Authors: Ogawa, Fumihiro, MD, PhD, Satoh, Yukitoshi, MD, PhD, Iyoda, Akira, MD, PhD, Amano, Hideki, MD, PhD, Kumagai, Yuji, MD, PhD, Majima, Masataka, MD, PhD
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - surgery; Comorbidity; Female; Humans; Logistic Models; Lung age; Lung Neoplasms - mortality; Lung Neoplasms - surgery; Male; Middle Aged; Non–small cell lung cancer; Patient Readmission - statistics & numerical data; Postoperative complications; Postoperative Complications - mortality; Predictive Value of Tests; Readmission; Respiratory Function Tests; Retrospective Studies; Risk Factors; Surgery; Surgical resection; Survival Rate
• ISSN: 0022-4804; 1095-8673
• DOI: 10.1016/j.jss.2014.08.028

Abstract Background Recently, the Japanese Respiratory Society (JRS) proposed using lung age (LA) as an indicator of lung function; however, reports regarding the association of LA with the risk of postoperative readmission within 90 d after surgical treatment for non–small cell lung cancer (NSCLC) are limited. Here, we analyze the clinical relationship between LA and readmission within 90 d after surgical treatment for NSCLC. Methods A total of 979 patients underwent curative resections for NSCLC from January 2000–September 2012 at the Kitasato University Hospital. We selected patients who required readmission because of surgical complications within 90 d of surgery and retrospectively analyzed various clinical data. LA was calculated based on the formula given by the Japanese Respiratory Society, which relies on preoperative respiratory function. We also calculated the age gap (AG) between the calculated LA and the true age (TA). Results There were 216 patients who needed to be readmitted within 90 d of surgery, 33 (3%) of whom were hospitalized for surgical complications. Twenty-four patients (73%) had respiratory complications, and 7 patients (21%) died. There were significant differences between the readmitted and no readmitted patients in terms of preoperative factors, such as gender, LA, AG, smoking status, and smoking index ( P