Independent brachytherapy plan verification software: Improving efficacy and efficiency

Abstract Background and purpose To compare the pre-treatment brachytherapy plan verification by a physicist assisted by custom plan verification software (SAV) with those performed manually (MV). Materials and methods All HDR brachytherapy plans used for treatment in 2013, verified using either SAV...

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Bibliographic Details
Published in:Radiotherapy and oncology 2014-12, Vol.113 (3), p.420-424
Main Authors: Damato, Antonio L, Devlin, Phillip M, Bhagwat, Mandar S, Buzurovic, Ivan, Friesen, Scott, Hansen, Jorgen L, Lee, Larissa J, Molodowitch, Christina, Nguyen, Paul L, O’Farrell, Desmond A, Viswanathan, Akila N, Williams, Christopher L, Killoran, Joseph H, Cormack, Robert A
Format: Article
Language:English
Subjects:
Brachytherapy - methods
Hematology, Oncology and Palliative Medicine
Humans
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted - methods
Reproducibility of Results
Retrospective Studies
Software Validation
Treatment Outcome
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Summary:Abstract Background and purpose To compare the pre-treatment brachytherapy plan verification by a physicist assisted by custom plan verification software (SAV) with those performed manually (MV). Materials and methods All HDR brachytherapy plans used for treatment in 2013, verified using either SAV or MV, were retrospectively reviewed. Error rate (number of errors/number of plans) was measured and verification time calculated. All HDR brachytherapy safety events recorded between 2010 and 2013 were identified. The rate of patient-related safety events (number of events/number of fractions treated) and the impact of SAV on the underlying errors were assessed. Results Three/106 errors (2.8%) were found in the SAV group and 24/273 (8.8%) in the MV group ( p = 0.046). The mean ±1 standard deviation plan verification time was 8.4 ± 4.0 min for SAV and 11.6 ± 5.3 for MV ( p = 0.006). Seven safety events out of 4729 fractions delivered (0.15%) were identified. Four events (57%) were associated with plan verification and could have been detected by SAV. Conclusions We found a safety event rate in HDR brachytherapy of 0.15%. SAV significantly reduced the number of undetected errors in HDR treatment plans compared to MV, and reduced the time required for plan verification.
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2014.09.015