Alterations in HPA-axis and autonomic nervous system functioning in childhood anxiety disorders point to a chronic stress hypothesis

Highlights • Children with AD have specific psychophysiological characteristics, which resemble the psychophysiological characteristics of chronic stress. • A high clinical burden is associated with altered ANS and HPA-axis functioning. • Children with specific phobia can be discerned from children...

Full description

Saved in:
Bibliographic Details
Published in:Psychoneuroendocrinology 2015-01, Vol.51, p.135-150
Main Authors: Dieleman, Gwendolyn C, Huizink, Anja C, Tulen, Joke H.M, Utens, Elisabeth M.W.J, Creemers, Hanneke E, van der Ende, Jan, Verhulst, Frank C
Format: Article
Language:English
Subjects:
Anxiety disorder
Anxiety Disorders - diagnosis
Anxiety Disorders - physiopathology
Autonomic nervous system
Autonomic Nervous System - physiopathology
Child
Circadian Rhythm - physiology
Comorbidity, Severity
Cortisol
Diagnosis, Differential
Endocrinology & Metabolism
Female
HPA-axis
Humans
Hydrocortisone - analysis
Hypothalamo-Hypophyseal System - physiopathology
Male
Pituitary-Adrenal System - physiopathology
Psychiatry
Psychophysiology
Saliva - chemistry
Stress, Perceived arousal
Stress, Psychological - physiopathology
Surveys and Questionnaires
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Children with AD have specific psychophysiological characteristics, which resemble the psychophysiological characteristics of chronic stress. • A high clinical burden is associated with altered ANS and HPA-axis functioning. • Children with specific phobia can be discerned from children with social phobia and separation anxiety disorder on higher skin conductance level.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2014.09.002