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Ultrasonographic findings of Kimura’s disease presenting in the upper extremities

Objective To describe ultrasound findings of Kimura’s disease arising in the upper extremities. Materials and methods Five patients with Kimura’s disease confirmed by surgical resection were retrospectively reviewed by two musculoskeletal radiologists and a pathologist. Results All six lesions invol...

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Bibliographic Details
Published in:Japanese journal of radiology 2014-12, Vol.32 (12), p.692-699
Main Authors: Shin, Gi Won, Lee, Sun Joo, Choo, Hye Jung, Park, Young Mi, Jeong, Hae Woong, Lee, Sung-Moon, Suh, Jin-Suck, Jung, Soo-Jin
Format: Article
Language:English
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Summary:Objective To describe ultrasound findings of Kimura’s disease arising in the upper extremities. Materials and methods Five patients with Kimura’s disease confirmed by surgical resection were retrospectively reviewed by two musculoskeletal radiologists and a pathologist. Results All six lesions involved the epitrochlear area and appeared as partially ( n  = 5) or poorly ( n  = 1) marginated subcutaneous masses with the presence of curvilinear hyperechoic bands intermingled within the hypoechoic components by US. Moderate ( n  = 4) to severe ( n  = 2) vascular signals were observed in some proportion of the hyperechoic bands by color Doppler US. The associated findings were the increased echogenicity of surrounding subcutaneous fat ( n  = 6) and adjacent lymphadenopathy ( n  = 4). Microscopic examination showed proliferation of lymphoid follicles with prominent germinal centers and intervening fibrosis. Conclusions In this study, Kimura’s disease arising in the upper extremities showed a partially defined hypoechoic subcutaneous mass with internal hyperechoic bands and moderate-to-severe vascularities, increased echogenicity of the surrounding subcutaneous fat and adjacent lymphadenopathy on US. Thus, when these US features are observed in the typical epitrochlear region of an Asian individual, especially if accompanied by peripheral eosinophilia, Kimura’s disease should be considered as a possible diagnosis.
ISSN:1867-1071
1867-108X
DOI:10.1007/s11604-014-0368-z