Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication

• Published in: Annals of surgical oncology 2015-01, Vol.22 (1), p.111-116
• Main Authors: Jung, Woo Sang, Kim, Jeong-Ah, Son, Eun Ju, Youk, Ji Hyun, Park, Cheong Soo
• Format: Article
• Language: English
• Subjects: Adult; Carcinoma, Papillary - diagnostic imaging; Carcinoma, Papillary - secondary; Carcinoma, Papillary - surgery; Elasticity Imaging Techniques - methods; Endocrine Tumors; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Staging; Oncology; Prognosis; Retrospective Studies; Surgery; Surgical Oncology; Thyroid Neoplasms - diagnostic imaging; Thyroid Neoplasms - pathology; Thyroid Neoplasms - surgery; Thyroidectomy
• ISSN: 1068-9265; 1534-4681
• DOI: 10.1245/s10434-014-3627-4

Purpose The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC). Methods Eighty-four LNs of 66 patients with PTC underwent B-mode ultrasonography (BUS) and SWE before ultrasound-guided fine-needle aspiration biopsy or preoperative evaluation. SWE elasticity indices (EI) of mean (E mean ), minimum (E min ), maximum (E max ) and the ratio of E mean in LNs and surrounding muscle (E mean−m ) were measured at the stiffest portion of LNs (kPa). SWE EI were correlated with the pathologic diagnosis and the histopathologic findings, including number and size of metastatic LNs, the ratio of the number of metastatic LN/dissected LN, and the presence of extranodal extension. Diagnostic performances of SWE EI and BUS for predicting LN metastasis were assessed using receiver operating curve analysis. Results All SWE EI were significantly higher in metastatic LNs than in benign LNs ( p