Loading…
Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication
Purpose The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC). Methods Eighty-four LNs of 66 patients with PTC unde...
Saved in:
| Published in: | Annals of surgical oncology 2015-01, Vol.22 (1), p.111-116 |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3 |
| container_end_page | 116 |
| container_issue | 1 |
| container_start_page | 111 |
| container_title | Annals of surgical oncology |
| container_volume | 22 |
| creator | Jung, Woo Sang Kim, Jeong-Ah Son, Eun Ju Youk, Ji Hyun Park, Cheong Soo |
| description | Purpose
The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC).
Methods
Eighty-four LNs of 66 patients with PTC underwent B-mode ultrasonography (BUS) and SWE before ultrasound-guided fine-needle aspiration biopsy or preoperative evaluation. SWE elasticity indices (EI) of mean (E
mean
), minimum (E
min
), maximum (E
max
) and the ratio of E
mean
in LNs and surrounding muscle (E
mean−m
) were measured at the stiffest portion of LNs (kPa). SWE EI were correlated with the pathologic diagnosis and the histopathologic findings, including number and size of metastatic LNs, the ratio of the number of metastatic LN/dissected LN, and the presence of extranodal extension. Diagnostic performances of SWE EI and BUS for predicting LN metastasis were assessed using receiver operating curve analysis.
Results
All SWE EI were significantly higher in metastatic LNs than in benign LNs (
p
|
| doi_str_mv | 10.1245/s10434-014-3627-4 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1639977834</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1639977834</sourcerecordid><originalsourceid>FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3</originalsourceid><addsrcrecordid>eNp1kdGK1DAUhoMo7jr6AN5IwJu9qZ40aZp6J8OoA6MuuOJlSNvTmSxtU5N22L6HD2xKd0UEr3LI_53_5OQn5CWDNywV2dvAQHCRABMJl2meiEfkkmXxRkjFHscapEqKVGYX5FkItwAs55A9JRepyAUoDpfk17cTGk9_mDPSXWvC6I7eDKeZ2p7uzqadzGhdT11Dt-jPtjItPczdcKJfXI30M46xxQQbFuLaDLZtjZ_pzWn2ztZ0a3xle9eZd6u5rew4031f4x01gRp67d2xd4tA993QRv9l3HPypDFtwBf354Z8_7C72X5KDl8_7rfvD0mVgRrjziorsAAl0gxEDU2pGp7XJZO5KAymvAJseAmFlDJvKi5ijVkUQIAsBfINuVp9B-9-ThhG3dlQYdyhRzcFzSQvijxXsXNDXv-D3rrJ9_F1C6VUJguZRoqtVOVdCB4bPXjbxR_RDPQSmV4j0zEyvUSmF-dX985T2WH9p-MhowikKxCi1B_R_zX6v66_ATJpoec</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1638856962</pqid></control><display><type>article</type><title>Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication</title><source>Springer Nature</source><creator>Jung, Woo Sang ; Kim, Jeong-Ah ; Son, Eun Ju ; Youk, Ji Hyun ; Park, Cheong Soo</creator><creatorcontrib>Jung, Woo Sang ; Kim, Jeong-Ah ; Son, Eun Ju ; Youk, Ji Hyun ; Park, Cheong Soo</creatorcontrib><description>Purpose
The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC).
Methods
Eighty-four LNs of 66 patients with PTC underwent B-mode ultrasonography (BUS) and SWE before ultrasound-guided fine-needle aspiration biopsy or preoperative evaluation. SWE elasticity indices (EI) of mean (E
mean
), minimum (E
min
), maximum (E
max
) and the ratio of E
mean
in LNs and surrounding muscle (E
mean−m
) were measured at the stiffest portion of LNs (kPa). SWE EI were correlated with the pathologic diagnosis and the histopathologic findings, including number and size of metastatic LNs, the ratio of the number of metastatic LN/dissected LN, and the presence of extranodal extension. Diagnostic performances of SWE EI and BUS for predicting LN metastasis were assessed using receiver operating curve analysis.
Results
All SWE EI were significantly higher in metastatic LNs than in benign LNs (
p
< 0.005). Combined E
mean
[area under the curve (AUC) 0.811] or E
min
(AUC 0.812) with BUS showed significantly higher AUC than BUS (0.738) for predicting metastatic LNs (
p
= 0.041 and 0.033, respectively). The number of positive LNs/dissected LNs and the largest LN size were significantly correlated with SWE EI (
p
< 0.05 and
p
< 0.005, respectively). Metastatic LNs with extranodal extension showed significantly higher SWE EI (
p
< 0.005) than those without extranodal extension.
Conclusions
Combined use of SWE and BUS was adjunctive to the diagnostic performance of BUS for the prediction of LN metastasis of PTC, and quantitative SWE could predict pathologic prognostic factors of LN metastasis of PTC.</description><identifier>ISSN: 1068-9265</identifier><identifier>EISSN: 1534-4681</identifier><identifier>DOI: 10.1245/s10434-014-3627-4</identifier><identifier>PMID: 24740830</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Adult ; Carcinoma, Papillary - diagnostic imaging ; Carcinoma, Papillary - secondary ; Carcinoma, Papillary - surgery ; Elasticity Imaging Techniques - methods ; Endocrine Tumors ; Female ; Follow-Up Studies ; Humans ; Lymphatic Metastasis ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neoplasm Staging ; Oncology ; Prognosis ; Retrospective Studies ; Surgery ; Surgical Oncology ; Thyroid Neoplasms - diagnostic imaging ; Thyroid Neoplasms - pathology ; Thyroid Neoplasms - surgery ; Thyroidectomy</subject><ispartof>Annals of surgical oncology, 2015-01, Vol.22 (1), p.111-116</ispartof><rights>Society of Surgical Oncology 2014</rights><rights>Society of Surgical Oncology 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3</citedby><cites>FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24740830$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jung, Woo Sang</creatorcontrib><creatorcontrib>Kim, Jeong-Ah</creatorcontrib><creatorcontrib>Son, Eun Ju</creatorcontrib><creatorcontrib>Youk, Ji Hyun</creatorcontrib><creatorcontrib>Park, Cheong Soo</creatorcontrib><title>Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication</title><title>Annals of surgical oncology</title><addtitle>Ann Surg Oncol</addtitle><addtitle>Ann Surg Oncol</addtitle><description>Purpose
The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC).
Methods
Eighty-four LNs of 66 patients with PTC underwent B-mode ultrasonography (BUS) and SWE before ultrasound-guided fine-needle aspiration biopsy or preoperative evaluation. SWE elasticity indices (EI) of mean (E
mean
), minimum (E
min
), maximum (E
max
) and the ratio of E
mean
in LNs and surrounding muscle (E
mean−m
) were measured at the stiffest portion of LNs (kPa). SWE EI were correlated with the pathologic diagnosis and the histopathologic findings, including number and size of metastatic LNs, the ratio of the number of metastatic LN/dissected LN, and the presence of extranodal extension. Diagnostic performances of SWE EI and BUS for predicting LN metastasis were assessed using receiver operating curve analysis.
Results
All SWE EI were significantly higher in metastatic LNs than in benign LNs (
p
< 0.005). Combined E
mean
[area under the curve (AUC) 0.811] or E
min
(AUC 0.812) with BUS showed significantly higher AUC than BUS (0.738) for predicting metastatic LNs (
p
= 0.041 and 0.033, respectively). The number of positive LNs/dissected LNs and the largest LN size were significantly correlated with SWE EI (
p
< 0.05 and
p
< 0.005, respectively). Metastatic LNs with extranodal extension showed significantly higher SWE EI (
p
< 0.005) than those without extranodal extension.
Conclusions
Combined use of SWE and BUS was adjunctive to the diagnostic performance of BUS for the prediction of LN metastasis of PTC, and quantitative SWE could predict pathologic prognostic factors of LN metastasis of PTC.</description><subject>Adult</subject><subject>Carcinoma, Papillary - diagnostic imaging</subject><subject>Carcinoma, Papillary - secondary</subject><subject>Carcinoma, Papillary - surgery</subject><subject>Elasticity Imaging Techniques - methods</subject><subject>Endocrine Tumors</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Oncology</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Thyroid Neoplasms - diagnostic imaging</subject><subject>Thyroid Neoplasms - pathology</subject><subject>Thyroid Neoplasms - surgery</subject><subject>Thyroidectomy</subject><issn>1068-9265</issn><issn>1534-4681</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp1kdGK1DAUhoMo7jr6AN5IwJu9qZ40aZp6J8OoA6MuuOJlSNvTmSxtU5N22L6HD2xKd0UEr3LI_53_5OQn5CWDNywV2dvAQHCRABMJl2meiEfkkmXxRkjFHscapEqKVGYX5FkItwAs55A9JRepyAUoDpfk17cTGk9_mDPSXWvC6I7eDKeZ2p7uzqadzGhdT11Dt-jPtjItPczdcKJfXI30M46xxQQbFuLaDLZtjZ_pzWn2ztZ0a3xle9eZd6u5rew4031f4x01gRp67d2xd4tA993QRv9l3HPypDFtwBf354Z8_7C72X5KDl8_7rfvD0mVgRrjziorsAAl0gxEDU2pGp7XJZO5KAymvAJseAmFlDJvKi5ijVkUQIAsBfINuVp9B-9-ThhG3dlQYdyhRzcFzSQvijxXsXNDXv-D3rrJ9_F1C6VUJguZRoqtVOVdCB4bPXjbxR_RDPQSmV4j0zEyvUSmF-dX985T2WH9p-MhowikKxCi1B_R_zX6v66_ATJpoec</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Jung, Woo Sang</creator><creator>Kim, Jeong-Ah</creator><creator>Son, Eun Ju</creator><creator>Youk, Ji Hyun</creator><creator>Park, Cheong Soo</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication</title><author>Jung, Woo Sang ; Kim, Jeong-Ah ; Son, Eun Ju ; Youk, Ji Hyun ; Park, Cheong Soo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Carcinoma, Papillary - diagnostic imaging</topic><topic>Carcinoma, Papillary - secondary</topic><topic>Carcinoma, Papillary - surgery</topic><topic>Elasticity Imaging Techniques - methods</topic><topic>Endocrine Tumors</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Oncology</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Thyroid Neoplasms - diagnostic imaging</topic><topic>Thyroid Neoplasms - pathology</topic><topic>Thyroid Neoplasms - surgery</topic><topic>Thyroidectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jung, Woo Sang</creatorcontrib><creatorcontrib>Kim, Jeong-Ah</creatorcontrib><creatorcontrib>Son, Eun Ju</creatorcontrib><creatorcontrib>Youk, Ji Hyun</creatorcontrib><creatorcontrib>Park, Cheong Soo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health Medical collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jung, Woo Sang</au><au>Kim, Jeong-Ah</au><au>Son, Eun Ju</au><au>Youk, Ji Hyun</au><au>Park, Cheong Soo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication</atitle><jtitle>Annals of surgical oncology</jtitle><stitle>Ann Surg Oncol</stitle><addtitle>Ann Surg Oncol</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>22</volume><issue>1</issue><spage>111</spage><epage>116</epage><pages>111-116</pages><issn>1068-9265</issn><eissn>1534-4681</eissn><abstract>Purpose
The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC).
Methods
Eighty-four LNs of 66 patients with PTC underwent B-mode ultrasonography (BUS) and SWE before ultrasound-guided fine-needle aspiration biopsy or preoperative evaluation. SWE elasticity indices (EI) of mean (E
mean
), minimum (E
min
), maximum (E
max
) and the ratio of E
mean
in LNs and surrounding muscle (E
mean−m
) were measured at the stiffest portion of LNs (kPa). SWE EI were correlated with the pathologic diagnosis and the histopathologic findings, including number and size of metastatic LNs, the ratio of the number of metastatic LN/dissected LN, and the presence of extranodal extension. Diagnostic performances of SWE EI and BUS for predicting LN metastasis were assessed using receiver operating curve analysis.
Results
All SWE EI were significantly higher in metastatic LNs than in benign LNs (
p
< 0.005). Combined E
mean
[area under the curve (AUC) 0.811] or E
min
(AUC 0.812) with BUS showed significantly higher AUC than BUS (0.738) for predicting metastatic LNs (
p
= 0.041 and 0.033, respectively). The number of positive LNs/dissected LNs and the largest LN size were significantly correlated with SWE EI (
p
< 0.05 and
p
< 0.005, respectively). Metastatic LNs with extranodal extension showed significantly higher SWE EI (
p
< 0.005) than those without extranodal extension.
Conclusions
Combined use of SWE and BUS was adjunctive to the diagnostic performance of BUS for the prediction of LN metastasis of PTC, and quantitative SWE could predict pathologic prognostic factors of LN metastasis of PTC.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>24740830</pmid><doi>10.1245/s10434-014-3627-4</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1068-9265 |
| ispartof | Annals of surgical oncology, 2015-01, Vol.22 (1), p.111-116 |
| issn | 1068-9265 1534-4681 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1639977834 |
| source | Springer Nature |
| subjects | Adult Carcinoma, Papillary - diagnostic imaging Carcinoma, Papillary - secondary Carcinoma, Papillary - surgery Elasticity Imaging Techniques - methods Endocrine Tumors Female Follow-Up Studies Humans Lymphatic Metastasis Male Medicine Medicine & Public Health Middle Aged Neoplasm Staging Oncology Prognosis Retrospective Studies Surgery Surgical Oncology Thyroid Neoplasms - diagnostic imaging Thyroid Neoplasms - pathology Thyroid Neoplasms - surgery Thyroidectomy |
| title | Shear Wave Elastography in Evaluation of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma: Elasticity Index as a Prognostic Implication |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-20T23%3A43%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Shear%20Wave%20Elastography%20in%20Evaluation%20of%20Cervical%20Lymph%20Node%20Metastasis%20of%20Papillary%20Thyroid%20Carcinoma:%20Elasticity%20Index%20as%20a%20Prognostic%20Implication&rft.jtitle=Annals%20of%20surgical%20oncology&rft.au=Jung,%20Woo%20Sang&rft.date=2015-01-01&rft.volume=22&rft.issue=1&rft.spage=111&rft.epage=116&rft.pages=111-116&rft.issn=1068-9265&rft.eissn=1534-4681&rft_id=info:doi/10.1245/s10434-014-3627-4&rft_dat=%3Cproquest_cross%3E1639977834%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c508t-36859e90842504d0fb8f37db16749ae23c0ef3b096667fc343b0e5ae20406b4e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1638856962&rft_id=info:pmid/24740830&rfr_iscdi=true |