Clinicopathologic Characteristics of Incidentally Identified Pheochromocytoma

ABSTRACT Background Pheochromocytomas are rare neuroendocrine tumors. With the widespread use of cross-sectional imaging, increasing numbers are identified incidentally, but their clinicopathologic traits have been incompletely characterized. Methods We performed a retrospective cohort study of pati...

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Bibliographic Details
Published in:Annals of surgical oncology 2015-01, Vol.22 (1), p.132-138
Main Authors: Wachtel, Heather, Cerullo, Isadora, Bartlett, Edmund K., Roses, Robert E., Cohen, Debbie L., Kelz, Rachel R., Karakousis, Giorgos C., Fraker, Douglas L.
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - pathology
Adrenal Gland Neoplasms - surgery
Adrenalectomy
Endocrine Tumors
Female
Follow-Up Studies
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Staging
Oncology
Pheochromocytoma - pathology
Pheochromocytoma - surgery
Postoperative Complications
Prognosis
Retrospective Studies
Surgery
Surgical Oncology
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Summary:ABSTRACT Background Pheochromocytomas are rare neuroendocrine tumors. With the widespread use of cross-sectional imaging, increasing numbers are identified incidentally, but their clinicopathologic traits have been incompletely characterized. Methods We performed a retrospective cohort study of patients who underwent initial adrenalectomy for pheochromocytoma (1997–2014). Patients were classified as identified by guided investigation (GIP) if imaging was performed for symptoms or surveillance and as incidentally identified pheochromocytomas (IIP) if imaging was performed for other indications. Student’s t test, Chi square test, or rank-sum tests were used as appropriate. Results Of 126 patients, 47 % were IIP ( n  = 59). IIP patients had more nonspecific symptoms, including abdominal or back pain (39.0 vs. 6.0 %, p  
ISSN:1068-9265
1534-4681
DOI:10.1245/s10434-014-3933-x