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Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analysis
Several case–control studies indicated that XRCC3 genetic polymorphism (C722T) was associated with larynx cancer. The present study aimed to further evaluate the relation between the XRCC3 gene C722T polymorphism and larynx cancer. We selected five case–control studies related to XRCC3 gene C722T po...
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| Published in: | Tumor biology 2014-06, Vol.35 (6), p.5427-5430 |
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| Main Authors: | , , , , |
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| container_end_page | 5430 |
| container_issue | 6 |
| container_start_page | 5427 |
| container_title | Tumor biology |
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| creator | Li, Dong You, Hui-Hua Jia, Yuan-Jing Guo, Jian-Dong Du, Huan-LE |
| description | Several case–control studies indicated that
XRCC3
genetic polymorphism (C722T) was associated with larynx cancer. The present study aimed to further evaluate the relation between the
XRCC3
gene C722T polymorphism and larynx cancer. We selected five case–control studies related to
XRCC3
gene C722T polymorphism and larynx cancer by searching PubMed, EMBase, Chinese CNKI, and Wanfang database. RevMan 5.0 software was used to perform the analysis. We directly utilized
Q
test and
I
2
test to test the heterogeneity between each study. We utilized the fixed effects model to merge the odds ratio (OR) and 95 % confidence interval. There were 1,507 larynx cancer patients and 3,623 cancer-free control subjects included in the present study. By meta-analysis, we did not find any association of
XRCC3
gene C722T polymorphism with larynx cancer [OR = 1.54, 95 % CI (0.77–3.08);
P
= 0.22]. The present study indicated that
XRCC3
gene C722T polymorphism was not associated with larynx cancer. |
| doi_str_mv | 10.1007/s13277-014-1707-5 |
| format | article |
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XRCC3
genetic polymorphism (C722T) was associated with larynx cancer. The present study aimed to further evaluate the relation between the
XRCC3
gene C722T polymorphism and larynx cancer. We selected five case–control studies related to
XRCC3
gene C722T polymorphism and larynx cancer by searching PubMed, EMBase, Chinese CNKI, and Wanfang database. RevMan 5.0 software was used to perform the analysis. We directly utilized
Q
test and
I
2
test to test the heterogeneity between each study. We utilized the fixed effects model to merge the odds ratio (OR) and 95 % confidence interval. There were 1,507 larynx cancer patients and 3,623 cancer-free control subjects included in the present study. By meta-analysis, we did not find any association of
XRCC3
gene C722T polymorphism with larynx cancer [OR = 1.54, 95 % CI (0.77–3.08);
P
= 0.22]. The present study indicated that
XRCC3
gene C722T polymorphism was not associated with larynx cancer.</description><identifier>ISSN: 1010-4283</identifier><identifier>EISSN: 1423-0380</identifier><identifier>DOI: 10.1007/s13277-014-1707-5</identifier><identifier>PMID: 24523020</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Cancer Research ; Case-Control Studies ; DNA-Binding Proteins - genetics ; Genes ; Genetic Predisposition to Disease ; Humans ; Laryngeal cancer ; Laryngeal Neoplasms - genetics ; Meta-analysis ; Polymorphism ; Polymorphism, Genetic ; Publication Bias ; Research Article</subject><ispartof>Tumor biology, 2014-06, Vol.35 (6), p.5427-5430</ispartof><rights>International Society of Oncology and BioMarkers (ISOBM) 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-a2a7545b171314a45a8d4f29dabc3f3d7169501bb8f258a86a3dfbc350abf16c3</citedby><cites>FETCH-LOGICAL-c475t-a2a7545b171314a45a8d4f29dabc3f3d7169501bb8f258a86a3dfbc350abf16c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1534723859?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,25752,27923,27924,37011,37012,44589</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24523020$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Dong</creatorcontrib><creatorcontrib>You, Hui-Hua</creatorcontrib><creatorcontrib>Jia, Yuan-Jing</creatorcontrib><creatorcontrib>Guo, Jian-Dong</creatorcontrib><creatorcontrib>Du, Huan-LE</creatorcontrib><title>Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analysis</title><title>Tumor biology</title><addtitle>Tumor Biol</addtitle><addtitle>Tumour Biol</addtitle><description>Several case–control studies indicated that
XRCC3
genetic polymorphism (C722T) was associated with larynx cancer. The present study aimed to further evaluate the relation between the
XRCC3
gene C722T polymorphism and larynx cancer. We selected five case–control studies related to
XRCC3
gene C722T polymorphism and larynx cancer by searching PubMed, EMBase, Chinese CNKI, and Wanfang database. RevMan 5.0 software was used to perform the analysis. We directly utilized
Q
test and
I
2
test to test the heterogeneity between each study. We utilized the fixed effects model to merge the odds ratio (OR) and 95 % confidence interval. There were 1,507 larynx cancer patients and 3,623 cancer-free control subjects included in the present study. By meta-analysis, we did not find any association of
XRCC3
gene C722T polymorphism with larynx cancer [OR = 1.54, 95 % CI (0.77–3.08);
P
= 0.22]. The present study indicated that
XRCC3
gene C722T polymorphism was not associated with larynx cancer.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cancer Research</subject><subject>Case-Control Studies</subject><subject>DNA-Binding Proteins - genetics</subject><subject>Genes</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Laryngeal cancer</subject><subject>Laryngeal Neoplasms - genetics</subject><subject>Meta-analysis</subject><subject>Polymorphism</subject><subject>Polymorphism, Genetic</subject><subject>Publication Bias</subject><subject>Research Article</subject><issn>1010-4283</issn><issn>1423-0380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNqFkV1rFTEQhoMo9kN_gDcS8Mab1Jl8bLLelUVtoSBoBe_C7G623bK7OSZ7aM-_N4dTRQTxKgPzzJtJHsZeIZwhgH2XUUlrBaAWaMEK84Qdo5ZKgHLwtNSAILR06oid5HwHgKauq-fsSGojFUg4Zl_Pc47dSOsYFx4H3lgpr_kmTrs5ps3tmGc-Lvz7l6ZR_CYsgd-P6y2fKO2WB97R0oX0nhOfw0qCFpp2ecwv2LOBphxePp6n7NvHD9fNhbj6_OmyOb8SnbZmFSTJGm1atKhQkzbkej3Iuqe2U4PqLVa1AWxbN0jjyFWk-qG0DFA7YNWpU_b2kLtJ8cc25NXPY-7CNNES4jZ7rFRd1-Cs-T9qykrSVA4K-uYv9C5uU3nanlLaSuVMXSg8UF2KOacw-E0a5_ItHsHv5fiDHF_k-L0cv1_i9WPytp1D_3vil40CyAOQS2u5CemPq_-Z-hNE4pcZ</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Li, Dong</creator><creator>You, Hui-Hua</creator><creator>Jia, Yuan-Jing</creator><creator>Guo, Jian-Dong</creator><creator>Du, Huan-LE</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>20140601</creationdate><title>Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analysis</title><author>Li, Dong ; You, Hui-Hua ; Jia, Yuan-Jing ; Guo, Jian-Dong ; Du, Huan-LE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-a2a7545b171314a45a8d4f29dabc3f3d7169501bb8f258a86a3dfbc350abf16c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cancer Research</topic><topic>Case-Control Studies</topic><topic>DNA-Binding Proteins - genetics</topic><topic>Genes</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Laryngeal cancer</topic><topic>Laryngeal Neoplasms - genetics</topic><topic>Meta-analysis</topic><topic>Polymorphism</topic><topic>Polymorphism, Genetic</topic><topic>Publication Bias</topic><topic>Research Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Dong</creatorcontrib><creatorcontrib>You, Hui-Hua</creatorcontrib><creatorcontrib>Jia, Yuan-Jing</creatorcontrib><creatorcontrib>Guo, Jian-Dong</creatorcontrib><creatorcontrib>Du, Huan-LE</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Tumor biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Dong</au><au>You, Hui-Hua</au><au>Jia, Yuan-Jing</au><au>Guo, Jian-Dong</au><au>Du, Huan-LE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analysis</atitle><jtitle>Tumor biology</jtitle><stitle>Tumor Biol</stitle><addtitle>Tumour Biol</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>35</volume><issue>6</issue><spage>5427</spage><epage>5430</epage><pages>5427-5430</pages><issn>1010-4283</issn><eissn>1423-0380</eissn><abstract>Several case–control studies indicated that
XRCC3
genetic polymorphism (C722T) was associated with larynx cancer. The present study aimed to further evaluate the relation between the
XRCC3
gene C722T polymorphism and larynx cancer. We selected five case–control studies related to
XRCC3
gene C722T polymorphism and larynx cancer by searching PubMed, EMBase, Chinese CNKI, and Wanfang database. RevMan 5.0 software was used to perform the analysis. We directly utilized
Q
test and
I
2
test to test the heterogeneity between each study. We utilized the fixed effects model to merge the odds ratio (OR) and 95 % confidence interval. There were 1,507 larynx cancer patients and 3,623 cancer-free control subjects included in the present study. By meta-analysis, we did not find any association of
XRCC3
gene C722T polymorphism with larynx cancer [OR = 1.54, 95 % CI (0.77–3.08);
P
= 0.22]. The present study indicated that
XRCC3
gene C722T polymorphism was not associated with larynx cancer.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>24523020</pmid><doi>10.1007/s13277-014-1707-5</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1010-4283 |
| ispartof | Tumor biology, 2014-06, Vol.35 (6), p.5427-5430 |
| issn | 1010-4283 1423-0380 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1639990875 |
| source | Publicly Available Content Database |
| subjects | Biomedical and Life Sciences Biomedicine Cancer Research Case-Control Studies DNA-Binding Proteins - genetics Genes Genetic Predisposition to Disease Humans Laryngeal cancer Laryngeal Neoplasms - genetics Meta-analysis Polymorphism Polymorphism, Genetic Publication Bias Research Article |
| title | Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analysis |
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