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Sex differences in behavior and pro-inflammatory cytokine mRNA expression following stressor exposure and re-exposure
Highlights • Males and females demonstrate markedly different plus maze behaviors, even 6 weeks after stressors. • Stressors elicit sensitized expression of IL-1β in males but not females. • Baseline sex differences for cytokine expression are found in the hippocampus.
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| Published in: | Neuroscience 2014-09, Vol.277, p.239-249 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c468t-43779bf73eb63d4676ed8cba65eee2401d8b3769c90a3dc5f48541b646f3d9703 |
| container_end_page | 249 |
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| container_start_page | 239 |
| container_title | Neuroscience |
| container_volume | 277 |
| creator | Hudson, S.P Jacobson-Pick, S Anisman, H |
| description | Highlights • Males and females demonstrate markedly different plus maze behaviors, even 6 weeks after stressors. • Stressors elicit sensitized expression of IL-1β in males but not females. • Baseline sex differences for cytokine expression are found in the hippocampus. |
| doi_str_mv | 10.1016/j.neuroscience.2014.07.007 |
| format | article |
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Jacobson-Pick, S ; Anisman, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-43779bf73eb63d4676ed8cba65eee2401d8b3769c90a3dc5f48541b646f3d9703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>anxiety</topic><topic>cytokine</topic><topic>Exploratory Behavior - physiology</topic><topic>Hippocampus - physiopathology</topic><topic>Interleukin-1beta - metabolism</topic><topic>Interleukin-6 - metabolism</topic><topic>Maze Learning</topic><topic>Mice</topic><topic>Neurology</topic><topic>Neuropsychological Tests</topic><topic>Prefrontal Cortex - physiopathology</topic><topic>Random Allocation</topic><topic>Receptors, Interleukin-1 - metabolism</topic><topic>Receptors, Interleukin-6 - metabolism</topic><topic>Receptors, Tumor Necrosis Factor - metabolism</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>RNA, Messenger - metabolism</topic><topic>Sex Characteristics</topic><topic>sex differences</topic><topic>stress</topic><topic>Stress, Psychological - physiopathology</topic><topic>Tumor Necrosis Factor-alpha - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hudson, S.P</creatorcontrib><creatorcontrib>Jacobson-Pick, S</creatorcontrib><creatorcontrib>Anisman, H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Animal Behavior Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hudson, S.P</au><au>Jacobson-Pick, S</au><au>Anisman, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sex differences in behavior and pro-inflammatory cytokine mRNA expression following stressor exposure and re-exposure</atitle><jtitle>Neuroscience</jtitle><addtitle>Neuroscience</addtitle><date>2014-09-26</date><risdate>2014</risdate><volume>277</volume><spage>239</spage><epage>249</epage><pages>239-249</pages><issn>0306-4522</issn><eissn>1873-7544</eissn><abstract>Highlights • Males and females demonstrate markedly different plus maze behaviors, even 6 weeks after stressors. • Stressors elicit sensitized expression of IL-1β in males but not females. • Baseline sex differences for cytokine expression are found in the hippocampus.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>25034513</pmid><doi>10.1016/j.neuroscience.2014.07.007</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0306-4522 |
| ispartof | Neuroscience, 2014-09, Vol.277, p.239-249 |
| issn | 0306-4522 1873-7544 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1639994819 |
| source | Elsevier:Jisc Collections:Elsevier Read and Publish Agreement 2022-2024:Freedom Collection (Reading list) |
| subjects | Animals anxiety cytokine Exploratory Behavior - physiology Hippocampus - physiopathology Interleukin-1beta - metabolism Interleukin-6 - metabolism Maze Learning Mice Neurology Neuropsychological Tests Prefrontal Cortex - physiopathology Random Allocation Receptors, Interleukin-1 - metabolism Receptors, Interleukin-6 - metabolism Receptors, Tumor Necrosis Factor - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Sex Characteristics sex differences stress Stress, Psychological - physiopathology Tumor Necrosis Factor-alpha - metabolism |
| title | Sex differences in behavior and pro-inflammatory cytokine mRNA expression following stressor exposure and re-exposure |
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