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Value of the “TAVI2 -SCORe” Versus Surgical Risk Scores for Prediction of One Year Mortality in 511 Patients Who Underwent Transcatheter Aortic Valve Implantation

A bedside-available transcatheter aortic valve implantation (TAVI)–dedicated prognostic risk score is an unmet clinical need. We aimed to develop such a risk score predicting 1-year mortality post-TAVI and to compare it with the performance of the logistic EuroSCORE (LES) I and LES-II and the Societ...

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Published in:The American journal of cardiology 2015-01, Vol.115 (2), p.234-242
Main Authors: Debonnaire, Philippe, MD, Fusini, Laura, MS, Wolterbeek, Ron, MD, Kamperidis, Vasileios, MD, van Rosendael, Philippe, MD, van der Kley, Frank, MD, Katsanos, Spyridon, MD, Joyce, Emer, MB, BCh, BAO, Tamborini, Gloria, MD, Muratori, Manuela, MD, Gripari, Paola, MD, Bax, Jeroen J., MD, PhD, Marsan, Nina Ajmone, MD, PhD, Pepi, Mauro, MD, PhD, Delgado, Victoria, MD, PhD
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Language:English
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Summary:A bedside-available transcatheter aortic valve implantation (TAVI)–dedicated prognostic risk score is an unmet clinical need. We aimed to develop such a risk score predicting 1-year mortality post-TAVI and to compare it with the performance of the logistic EuroSCORE (LES) I and LES-II and the Society of Thoracic Surgeons' (STS) score. Baseline variables of 511 consecutive patients who underwent TAVI that were independently associated with 1-year mortality post-TAVI were included in the “TAVI2 -SCORe.” Discrimination and calibration abilities of the novel score were assessed and compared with surgical risk scores. One-year mortality was 17.0% (n = 80 of 471). Porcelain thoracic aorta (hazard ratio [HR] 2.56), anemia (HR 2.03), left ventricular dysfunction (HR 1.98), recent myocardial infarction (HR 3.78), male sex (HR 1.81), critical aortic valve stenosis (HR 2.46), old age (HR 1.68), and renal dysfunction (HR 1.76) formed the TAVI2 -SCORe (all p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2014.10.029