MRI findings in pediatric patients with scurvy

In modern times scurvy is a rarely encountered disease caused by ascorbic acid (vitamin C) deficiency. However, sporadic cases of scurvy persist, particularly within the pediatric population. Recent individual case reports highlight an increased incidence of scurvy among patients with autism or deve...

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Bibliographic Details
Published in:Skeletal radiology 2015-02, Vol.44 (2), p.291-297
Main Authors: Gulko, Edwin, Collins, Lee K., Murphy, Robyn C., Thornhill, Beverly A., Taragin, Benjamin H.
Format: Article
Language:English
Subjects:
Autism
Bone and Bones - pathology
Bone Diseases, Developmental - complications
Bone Diseases, Developmental - pathology
Bone Diseases, Metabolic - complications
Bone Diseases, Metabolic - pathology
Case Report
Child
Child, Preschool
Children
Diagnosis, Differential
Health aspects
Humans
Imaging
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Nuclear Medicine
Orthopedics
Pathology
Pediatrics
Radiology
Scurvy
Scurvy - complications
Scurvy - pathology
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Summary:In modern times scurvy is a rarely encountered disease caused by ascorbic acid (vitamin C) deficiency. However, sporadic cases of scurvy persist, particularly within the pediatric population. Recent individual case reports highlight an increased incidence of scurvy among patients with autism or developmental delay, with isolated case reports detailing the magnetic resonance imaging (MRI) findings of scurvy in these pediatric populations. We present the MRI findings of scurvy in four patients with autism or developmental delay, and review the literature on MRI findings in pediatric patients with scurvy. Despite its rarity, the radiologist must consider scurvy in a pediatric patient with a restricted diet presenting with arthralgia or myalgia.
ISSN:0364-2348
1432-2161
DOI:10.1007/s00256-014-1962-y