Late-onset Peripheral Ulcerative Sclerokeratitis Associated With Alkali Chemical Burn

Hyperbaric oxygen supports oxygen-dependent collagen synthesis and attenuates cell apoptosis.2 Furthermore, it has been reported that hyperbaric oxygen can control inflammation and vasculogenesis by decreasing neutrophil adherence and downregulating the expression of intercellular adhesion molecule-...

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Bibliographic Details
Published in:American journal of ophthalmology 2015-02, Vol.159 (2), p.407-408
Main Authors: Ilhan, Abdullah, Tas, Ahmet, Yolcu, Umit, Erdem, Uzeyir, Altun, Salih
Format: Article
Language:English
Subjects:
Alkalies - adverse effects
Burns, Chemical - etiology
Cerebral palsy
Corneal Ulcer - etiology
Eye Burns - chemically induced
Humans
Ischemia
Male
Ophthalmology
Oxygen
Oxygen therapy
Scleritis - etiology
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Summary:Hyperbaric oxygen supports oxygen-dependent collagen synthesis and attenuates cell apoptosis.2 Furthermore, it has been reported that hyperbaric oxygen can control inflammation and vasculogenesis by decreasing neutrophil adherence and downregulating the expression of intercellular adhesion molecule-1 and vascular endothelial growth factor.3 Hyperbaric oxygen can improve the potency of antibiotics and has antibacterial effects as well.4 Finally, hyperbaric oxygen stimulates the defense mechanisms against oxidative stress that plays a critical role in chemical injuries such as mustard-induced burns.5 Regarding the features of hyperbaric oxygen noted above, we suppose that hyperbaric oxygen therapy would be advantageous in the treatment of PUK.
ISSN:0002-9394
1879-1891
DOI:10.1016/j.ajo.2014.11.019