Cleft palate: A clinical review

Orofacial clefts, including cleft palates (CP), are one of the most common birth defects. CP have a multiplicity of effects on the individual and society in terms of economic costs, loss of productivity, psychosocial effects, and increased morbidity and mortality at all stages of life. Embryological...

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Bibliographic Details
Published in:Birth defects research. Part C. Embryo today 2014-12, Vol.102 (4), p.333-342
Main Authors: Shkoukani, Mahdi A., Lawrence, Lauren A., Liebertz, Daniel J., Svider, Peter F.
Format: Article
Language:English
Subjects:
Abnormalities, Multiple
cleft palate
Cleft Palate - diagnosis
Cleft Palate - psychology
Cleft Palate - therapy
congenital anomalies
craniofacial anomalies
Humans
orofacial cleft
Quality of Life
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Summary:Orofacial clefts, including cleft palates (CP), are one of the most common birth defects. CP have a multiplicity of effects on the individual and society in terms of economic costs, loss of productivity, psychosocial effects, and increased morbidity and mortality at all stages of life. Embryological development of the palate is well delineated, with developments in the last decade regarding the biomolecular processes involved. Etiology is complex, involving a number of genetic and environmental factors. Various techniques can be employed for the repair of CP, depending on whether the cleft is of the primary or secondary palate, the width of the cleft, whether lengthening of the palate is necessary, and with regard to concerns of disruption of midfacial growth. All surgical techniques have the goals of restoring functional speech, swallowing, and aesthetics. A multidisciplinary team is necessary for the long‐term pre‐ and postoperative care of CP patients to handle complications, associated anomalies, and to optimize function and quality of life. Birth Defects Research (Part C) 102:333–342, 2014. © 2014 Wiley Periodicals, Inc.
ISSN:1542-975X
1542-9768
DOI:10.1002/bdrc.21083