Diminished ovarian reserve in Behçet’s disease patients

This study aims to assess ovarian reserve markers in Behçet's disease (BD) patients. Ten BD and 22 healthy controls were evaluated for ovarian reserve by examining the levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, inhibin B, total morning testosterone, prola...

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Bibliographic Details
Published in:Clinical rheumatology 2015-01, Vol.34 (1), p.179-183
Main Authors: Mont’Alverne, Andrea R. S., Yamakami, Lucas Y. S., Gonçalves, Célio R., Baracat, Edmund C., Bonfá, Eloisa, Silva, Clovis A.
Format: Article
Language:English
Subjects:
Adult
Anti-Mullerian Hormone - blood
Behcet Syndrome - blood
Behcet Syndrome - physiopathology
Brief Report
Estradiol - blood
Female
Follicle Stimulating Hormone - blood
Humans
Inhibins - blood
Luteinizing Hormone - blood
Medicine
Medicine & Public Health
Middle Aged
Ovarian Follicle
Ovarian Reserve - physiology
Prolactin - blood
Rheumatology
Testosterone - blood
Thyrotropin - blood
Young Adult
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Summary:This study aims to assess ovarian reserve markers in Behçet's disease (BD) patients. Ten BD and 22 healthy controls were evaluated for ovarian reserve by examining the levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, inhibin B, total morning testosterone, prolactin, thyroid-stimulating hormone (TSH), and antral follicle count. Anti-Müllerian hormone (AMH) was measured using two different enzyme-linked immunosorbent assay (ELISA) kits. Demographic data, menstrual abnormalities, disease parameters, and treatments were also analyzed. The median current age was similar in BD patients and controls (34 (20–40) vs. 31.3 (20–42) years, p  = 0.33). A positive correlation was observed between the AMH Gen II ELISA and AMH/MISAnshLabs ELISA assays in the BD patients ( r  = +0.98; p  
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-014-2680-5