Pheochromocytoma and paraganglioma in childhood: a report of 2 cases report

• Published in: Anales de pediatría (Barcelona, Spain : 2003) Spain : 2003), 2015-01, Vol.82 (1), p.e175-e180
• Main Authors: Mosquera Gorostidi, A, Justo Ranera, A, Zakirian Denis, S E, González Temprano, N, Sagaseta de Ilúrdoz Uranga, M, Molina Garicano, J
• Format: Article
• Language: Spanish
• Subjects: Adolescent; Adrenal Gland Neoplasms - diagnosis; Adrenal Gland Neoplasms - therapy; Female; Humans; Paraganglioma - diagnosis; Paraganglioma - therapy; Pheochromocytoma - diagnosis; Pheochromocytoma - therapy
• ISSN: 1695-9531
• DOI: 10.1016/j.anpedi.2014.06.018

Pheochromocytomas and paragangliomas are rare neuroendocrine tumors in children and most of them are sporadic. However, they represent the most common endocrine tumor in childhood, and hereditary tumor syndromes are most relevant in these age. Advances in genetic, biochemistry and imaging techniques have revised the management of these tumors; thus A biochemical study should be always initiated once the clinical diagnosis is suspected, followed by imaging and molecular studies, particularly in the context of known familial disease. The diagnostic and therapeutic features are reviewed after the presentation of two clinical cases, where the second one is a patient with type 1 Neurofibromatosis.