Antibacterial Properties of Ti-6Al-4V-xCu Alloys

Surgical implant-associated bacterial infection is becoming a serious clinical problem. A series of copper-bearing titanium alloy, Ti-6Al-4V-xCu （x = 1, 3, 5 wt%）, were fabricated in the present study in order to reduce the hazard of the bacterial infection problem by means of the strong antibacteri...

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Bibliographic Details
Published in:Journal of materials science & technology 2014, Vol.30 (7), p.699-705
Main Authors: Ren, Ling, Ma, Zheng, Li, Mei, Zhang, Yu, Liu, Weiqiang, Liao, Zhenhua, Yang, Ke
Format: Article
Language:English
Subjects:
Alloys
Antibacterial property
Antiinfectives and antibacterials
Bacteria
Biocompatibility
Copper
CORROSION
CORROSION PROTECTION
Corrosion resistance
Cu-bearing titanium alloy
METALLOGRAPHY
MICRO ORGANISMS
Surgical implants
Ti-6AL-4V合金
Titanium base alloys
Ti–6Al–4V
X射线衍射
临床应用
外科植入
抗菌性能
抗菌能力
细菌感染
铜钛合金
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Summary:Surgical implant-associated bacterial infection is becoming a serious clinical problem. A series of copper-bearing titanium alloy, Ti-6Al-4V-xCu （x = 1, 3, 5 wt%）, were fabricated in the present study in order to reduce the hazard of the bacterial infection problem by means of the strong antibacterial ability of Cu element. The metallography, X-ray diffraction, antibacterial ability, corrosion resistance and cytotoxicity of Ti-6Al-4V-xCu alloys were preliminarily studied with comparison to the commercial medical Ti-6Al-4V alloy. The Ti-6Al- 4V-xCu alloys showed obvious antibacterial abilities with good corrosion resistance and cytocompatibility, and the antibacterial role was enhanced with increasing Cu content, which has significant potential for clinical applications as surgical implant materials.
ISSN:1005-0302
1941-1162
DOI:10.1016/j.jmst.2013.12.014