Loading…
High prevalence of carbapenem resistance among plasmid-mediated AmpC β-lactamase-producing Klebsiella pneumoniae during outbreaks in liver transplantation units
Highlights • Outbreaks due to DHA-1-or CMY-2-producing K. pneumoniae strains occurred. • Carbamenem resistant variants with porin loss were frequently found. • Outbreak strains caused bloodstream infections with high mortality.
Saved in:
| Published in: | International journal of antimicrobial agents 2015-01, Vol.45 (1), p.33-40 |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63 |
| container_end_page | 40 |
| container_issue | 1 |
| container_start_page | 33 |
| container_title | International journal of antimicrobial agents |
| container_volume | 45 |
| creator | Matsumura, Yasufumi Tanaka, Michio Yamamoto, Masaki Nagao, Miki Machida, Kiyomasa Ito, Yutaka Takakura, Shunji Ogawa, Kohei Yoshizawa, Atsushi Fujimoto, Yasuhiro Okamoto, Shinya Uemoto, Shinji Ichiyama, Satoshi |
| description | Highlights • Outbreaks due to DHA-1-or CMY-2-producing K. pneumoniae strains occurred. • Carbamenem resistant variants with porin loss were frequently found. • Outbreak strains caused bloodstream infections with high mortality. |
| doi_str_mv | 10.1016/j.ijantimicag.2014.08.015 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1642607960</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0924857914003008</els_id><sourcerecordid>1642607960</sourcerecordid><originalsourceid>FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63</originalsourceid><addsrcrecordid>eNqNkkGO1DAQRS0EYoaGKyCzY5Om7NiJs0EatYBBjMSC2VuOXd24J3GC7bQ0x-EKHIQz4agHhFix8qKef1X9X4S8YrBlwJo3x60_mpD96K05bDkwsQW1BSYfkUumWl61Hasfk0vouKiUbLsL8iylIxSiFvIpueBSSKkkXJLv1_7wlc4RT2bAYJFOe2pN7M2MAUcaMfmUzVow4xQOdB5MGr2rRnTeZHT0apx39OePajA2m9EkrOY4ucX6An8asE8eh8HQOeBSBLxB6pa4Fqcl9xHNXaI-0MGfMNIcTUilQ8gm-ynQJficnpMnezMkfPHwbsjt-3e3u-vq5vOHj7urm8qKmucKW7GXAnivatHWtgcnsWs7xYQSqpF1C2A4N865jjvOXNvsBTiHaFFJ29Qb8vosW8b_tmDKevTJrrMHnJakWSN4A23XQEG7M2rjlFLEvZ6jH0281wz0GpA-6r8C0mtAGpRe7d-Qlw9tlr54-Ofn70QKsDsDWHY9eYw6Wb8m43xEm7Wb_H-1efuPih18KNhwh_eYjtMSQzFTM524Bv1lvZT1UJgAqAFU_QvnOMG1</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1642607960</pqid></control><display><type>article</type><title>High prevalence of carbapenem resistance among plasmid-mediated AmpC β-lactamase-producing Klebsiella pneumoniae during outbreaks in liver transplantation units</title><source>ScienceDirect Journals</source><creator>Matsumura, Yasufumi ; Tanaka, Michio ; Yamamoto, Masaki ; Nagao, Miki ; Machida, Kiyomasa ; Ito, Yutaka ; Takakura, Shunji ; Ogawa, Kohei ; Yoshizawa, Atsushi ; Fujimoto, Yasuhiro ; Okamoto, Shinya ; Uemoto, Shinji ; Ichiyama, Satoshi</creator><creatorcontrib>Matsumura, Yasufumi ; Tanaka, Michio ; Yamamoto, Masaki ; Nagao, Miki ; Machida, Kiyomasa ; Ito, Yutaka ; Takakura, Shunji ; Ogawa, Kohei ; Yoshizawa, Atsushi ; Fujimoto, Yasuhiro ; Okamoto, Shinya ; Uemoto, Shinji ; Ichiyama, Satoshi</creatorcontrib><description>Highlights • Outbreaks due to DHA-1-or CMY-2-producing K. pneumoniae strains occurred. • Carbamenem resistant variants with porin loss were frequently found. • Outbreak strains caused bloodstream infections with high mortality.</description><identifier>ISSN: 0924-8579</identifier><identifier>EISSN: 1872-7913</identifier><identifier>DOI: 10.1016/j.ijantimicag.2014.08.015</identifier><identifier>PMID: 25455850</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adult ; Aged ; AmpC ; Anti-Bacterial Agents - pharmacology ; Bacteremia - epidemiology ; Bacteremia - microbiology ; Bacterial Proteins - genetics ; beta-Lactam Resistance ; beta-Lactamases - genetics ; Carbapenems ; Carbapenems - pharmacology ; Case-Control Studies ; Disease Outbreaks ; DNA, Bacterial - genetics ; Female ; Hospitals, University ; Humans ; Infection Control ; Infectious Disease ; Japan ; Klebsiella Infections - epidemiology ; Klebsiella Infections - microbiology ; Klebsiella pneumoniae - drug effects ; Klebsiella pneumoniae - isolation & purification ; Liver Transplantation ; Male ; Middle Aged ; Molecular epidemiology ; Multilocus Sequence Typing ; Outer membrane protein ; Plasmids ; Polymerase Chain Reaction ; Young Adult</subject><ispartof>International journal of antimicrobial agents, 2015-01, Vol.45 (1), p.33-40</ispartof><rights>Elsevier B.V. and the International Society of Chemotherapy</rights><rights>2014 Elsevier B.V. and the International Society of Chemotherapy</rights><rights>Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63</citedby><cites>FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25455850$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Matsumura, Yasufumi</creatorcontrib><creatorcontrib>Tanaka, Michio</creatorcontrib><creatorcontrib>Yamamoto, Masaki</creatorcontrib><creatorcontrib>Nagao, Miki</creatorcontrib><creatorcontrib>Machida, Kiyomasa</creatorcontrib><creatorcontrib>Ito, Yutaka</creatorcontrib><creatorcontrib>Takakura, Shunji</creatorcontrib><creatorcontrib>Ogawa, Kohei</creatorcontrib><creatorcontrib>Yoshizawa, Atsushi</creatorcontrib><creatorcontrib>Fujimoto, Yasuhiro</creatorcontrib><creatorcontrib>Okamoto, Shinya</creatorcontrib><creatorcontrib>Uemoto, Shinji</creatorcontrib><creatorcontrib>Ichiyama, Satoshi</creatorcontrib><title>High prevalence of carbapenem resistance among plasmid-mediated AmpC β-lactamase-producing Klebsiella pneumoniae during outbreaks in liver transplantation units</title><title>International journal of antimicrobial agents</title><addtitle>Int J Antimicrob Agents</addtitle><description>Highlights • Outbreaks due to DHA-1-or CMY-2-producing K. pneumoniae strains occurred. • Carbamenem resistant variants with porin loss were frequently found. • Outbreak strains caused bloodstream infections with high mortality.</description><subject>Adult</subject><subject>Aged</subject><subject>AmpC</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Bacteremia - epidemiology</subject><subject>Bacteremia - microbiology</subject><subject>Bacterial Proteins - genetics</subject><subject>beta-Lactam Resistance</subject><subject>beta-Lactamases - genetics</subject><subject>Carbapenems</subject><subject>Carbapenems - pharmacology</subject><subject>Case-Control Studies</subject><subject>Disease Outbreaks</subject><subject>DNA, Bacterial - genetics</subject><subject>Female</subject><subject>Hospitals, University</subject><subject>Humans</subject><subject>Infection Control</subject><subject>Infectious Disease</subject><subject>Japan</subject><subject>Klebsiella Infections - epidemiology</subject><subject>Klebsiella Infections - microbiology</subject><subject>Klebsiella pneumoniae - drug effects</subject><subject>Klebsiella pneumoniae - isolation & purification</subject><subject>Liver Transplantation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Molecular epidemiology</subject><subject>Multilocus Sequence Typing</subject><subject>Outer membrane protein</subject><subject>Plasmids</subject><subject>Polymerase Chain Reaction</subject><subject>Young Adult</subject><issn>0924-8579</issn><issn>1872-7913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNkkGO1DAQRS0EYoaGKyCzY5Om7NiJs0EatYBBjMSC2VuOXd24J3GC7bQ0x-EKHIQz4agHhFix8qKef1X9X4S8YrBlwJo3x60_mpD96K05bDkwsQW1BSYfkUumWl61Hasfk0vouKiUbLsL8iylIxSiFvIpueBSSKkkXJLv1_7wlc4RT2bAYJFOe2pN7M2MAUcaMfmUzVow4xQOdB5MGr2rRnTeZHT0apx39OePajA2m9EkrOY4ucX6An8asE8eh8HQOeBSBLxB6pa4Fqcl9xHNXaI-0MGfMNIcTUilQ8gm-ynQJficnpMnezMkfPHwbsjt-3e3u-vq5vOHj7urm8qKmucKW7GXAnivatHWtgcnsWs7xYQSqpF1C2A4N865jjvOXNvsBTiHaFFJ29Qb8vosW8b_tmDKevTJrrMHnJakWSN4A23XQEG7M2rjlFLEvZ6jH0281wz0GpA-6r8C0mtAGpRe7d-Qlw9tlr54-Ofn70QKsDsDWHY9eYw6Wb8m43xEm7Wb_H-1efuPih18KNhwh_eYjtMSQzFTM524Bv1lvZT1UJgAqAFU_QvnOMG1</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Matsumura, Yasufumi</creator><creator>Tanaka, Michio</creator><creator>Yamamoto, Masaki</creator><creator>Nagao, Miki</creator><creator>Machida, Kiyomasa</creator><creator>Ito, Yutaka</creator><creator>Takakura, Shunji</creator><creator>Ogawa, Kohei</creator><creator>Yoshizawa, Atsushi</creator><creator>Fujimoto, Yasuhiro</creator><creator>Okamoto, Shinya</creator><creator>Uemoto, Shinji</creator><creator>Ichiyama, Satoshi</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>High prevalence of carbapenem resistance among plasmid-mediated AmpC β-lactamase-producing Klebsiella pneumoniae during outbreaks in liver transplantation units</title><author>Matsumura, Yasufumi ; Tanaka, Michio ; Yamamoto, Masaki ; Nagao, Miki ; Machida, Kiyomasa ; Ito, Yutaka ; Takakura, Shunji ; Ogawa, Kohei ; Yoshizawa, Atsushi ; Fujimoto, Yasuhiro ; Okamoto, Shinya ; Uemoto, Shinji ; Ichiyama, Satoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>AmpC</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Bacteremia - epidemiology</topic><topic>Bacteremia - microbiology</topic><topic>Bacterial Proteins - genetics</topic><topic>beta-Lactam Resistance</topic><topic>beta-Lactamases - genetics</topic><topic>Carbapenems</topic><topic>Carbapenems - pharmacology</topic><topic>Case-Control Studies</topic><topic>Disease Outbreaks</topic><topic>DNA, Bacterial - genetics</topic><topic>Female</topic><topic>Hospitals, University</topic><topic>Humans</topic><topic>Infection Control</topic><topic>Infectious Disease</topic><topic>Japan</topic><topic>Klebsiella Infections - epidemiology</topic><topic>Klebsiella Infections - microbiology</topic><topic>Klebsiella pneumoniae - drug effects</topic><topic>Klebsiella pneumoniae - isolation & purification</topic><topic>Liver Transplantation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Molecular epidemiology</topic><topic>Multilocus Sequence Typing</topic><topic>Outer membrane protein</topic><topic>Plasmids</topic><topic>Polymerase Chain Reaction</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Matsumura, Yasufumi</creatorcontrib><creatorcontrib>Tanaka, Michio</creatorcontrib><creatorcontrib>Yamamoto, Masaki</creatorcontrib><creatorcontrib>Nagao, Miki</creatorcontrib><creatorcontrib>Machida, Kiyomasa</creatorcontrib><creatorcontrib>Ito, Yutaka</creatorcontrib><creatorcontrib>Takakura, Shunji</creatorcontrib><creatorcontrib>Ogawa, Kohei</creatorcontrib><creatorcontrib>Yoshizawa, Atsushi</creatorcontrib><creatorcontrib>Fujimoto, Yasuhiro</creatorcontrib><creatorcontrib>Okamoto, Shinya</creatorcontrib><creatorcontrib>Uemoto, Shinji</creatorcontrib><creatorcontrib>Ichiyama, Satoshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of antimicrobial agents</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matsumura, Yasufumi</au><au>Tanaka, Michio</au><au>Yamamoto, Masaki</au><au>Nagao, Miki</au><au>Machida, Kiyomasa</au><au>Ito, Yutaka</au><au>Takakura, Shunji</au><au>Ogawa, Kohei</au><au>Yoshizawa, Atsushi</au><au>Fujimoto, Yasuhiro</au><au>Okamoto, Shinya</au><au>Uemoto, Shinji</au><au>Ichiyama, Satoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High prevalence of carbapenem resistance among plasmid-mediated AmpC β-lactamase-producing Klebsiella pneumoniae during outbreaks in liver transplantation units</atitle><jtitle>International journal of antimicrobial agents</jtitle><addtitle>Int J Antimicrob Agents</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>45</volume><issue>1</issue><spage>33</spage><epage>40</epage><pages>33-40</pages><issn>0924-8579</issn><eissn>1872-7913</eissn><abstract>Highlights • Outbreaks due to DHA-1-or CMY-2-producing K. pneumoniae strains occurred. • Carbamenem resistant variants with porin loss were frequently found. • Outbreak strains caused bloodstream infections with high mortality.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>25455850</pmid><doi>10.1016/j.ijantimicag.2014.08.015</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0924-8579 |
| ispartof | International journal of antimicrobial agents, 2015-01, Vol.45 (1), p.33-40 |
| issn | 0924-8579 1872-7913 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1642607960 |
| source | ScienceDirect Journals |
| subjects | Adult Aged AmpC Anti-Bacterial Agents - pharmacology Bacteremia - epidemiology Bacteremia - microbiology Bacterial Proteins - genetics beta-Lactam Resistance beta-Lactamases - genetics Carbapenems Carbapenems - pharmacology Case-Control Studies Disease Outbreaks DNA, Bacterial - genetics Female Hospitals, University Humans Infection Control Infectious Disease Japan Klebsiella Infections - epidemiology Klebsiella Infections - microbiology Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - isolation & purification Liver Transplantation Male Middle Aged Molecular epidemiology Multilocus Sequence Typing Outer membrane protein Plasmids Polymerase Chain Reaction Young Adult |
| title | High prevalence of carbapenem resistance among plasmid-mediated AmpC β-lactamase-producing Klebsiella pneumoniae during outbreaks in liver transplantation units |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T08%3A14%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=High%20prevalence%20of%20carbapenem%20resistance%20among%20plasmid-mediated%20AmpC%20%CE%B2-lactamase-producing%20Klebsiella%20pneumoniae%20during%20outbreaks%20in%20liver%20transplantation%20units&rft.jtitle=International%20journal%20of%20antimicrobial%20agents&rft.au=Matsumura,%20Yasufumi&rft.date=2015-01-01&rft.volume=45&rft.issue=1&rft.spage=33&rft.epage=40&rft.pages=33-40&rft.issn=0924-8579&rft.eissn=1872-7913&rft_id=info:doi/10.1016/j.ijantimicag.2014.08.015&rft_dat=%3Cproquest_cross%3E1642607960%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c432t-e74f5402b83473cb0d5e979814848653700a22addd92d21d76f40ddeece85c63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1642607960&rft_id=info:pmid/25455850&rfr_iscdi=true |