Eos, Goddess of Treg Cell Reprogramming

Under certain conditions, Sharma et al. (2013) show in this issue of Immunity that a subpopulation of Foxp3+ regulatory T cells loses expression of the transcription factor Eos and develops into Foxp3+ T helper cells that facilitate priming of naive CD8+ T cells.

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Bibliographic Details
Published in:Immunity (Cambridge, Mass.) Mass.), 2013-05, Vol.38 (5), p.849-850
Main Authors: Rieder, Sadiye Amcaoglu, Shevach, Ethan M.
Format: Article
Language:English
Subjects:
Animals
Carrier Proteins - metabolism
Cytokines
Genes
Ikaros Transcription Factor - metabolism
Inflammatory bowel disease
Interleukin-6 - metabolism
Lymphocytes
Nerve Tissue Proteins - metabolism
Studies
T-Lymphocytes, Helper-Inducer - immunology
Transcription factors
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Description
Summary:Under certain conditions, Sharma et al. (2013) show in this issue of Immunity that a subpopulation of Foxp3+ regulatory T cells loses expression of the transcription factor Eos and develops into Foxp3+ T helper cells that facilitate priming of naive CD8+ T cells.
ISSN:1074-7613
1097-4180
DOI:10.1016/j.immuni.2013.05.001