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Fibrosing mediastinitis mimicking sarcoidosis

Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the lo...

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Bibliographic Details
Published in:The clinical respiratory journal 2015-01, Vol.9 (1), p.125-128
Main Authors: Galván, Marta Ferrer, Portal, José Antonio Rodríguez, Gorarredona, María Pilar Serrano, Izquierdo, Lourdes Gómez
Format: Article
Language:English
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Summary:Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the location and extent of fibrosis. The cause is not always known but is often the result of a granulomatous disease, most often the histoplasmosis. We report a 43‐year‐old woman with a history of tuberculosis infection 23 years ago. She attended the pulmonology clinic for cough and dyspnea. Physical examination revealed jugular venous distention at 90°. In computed tomography scan of the chest with constrast (c/c), we observed a mediastinal nodal cast provoking cava compression and obliteration of main and intermediary right lobar bronchus. The pathological examination was FM.
ISSN:1752-6981
1752-699X
DOI:10.1111/crj.12107