Oral Ciprofloxacin Therapy for Bacillus cereus Wound Infection and Bacteremia

Bacillus cereus is a ubiquitous gram-positive rod found in soil. It is usually nonpathogenic, although serious infections may occur. Serious infections caused by B. cereus are related to toxin production and occur following operative procedures, traumatic wounds, and burns. B. cereus wound infection...

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Bibliographic Details
Published in:Clinical infectious diseases 1993-01, Vol.16 (1), p.189-189
Main Authors: Kemmerly, Sandra Abadie, Pankey, George A.
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Bacillus cereus
Bacillus cereus - drug effects
Bacillus cereus - isolation & purification
Bacteremia
Bacteremia - drug therapy
Ciprofloxacin - administration & dosage
Ciprofloxacin - therapeutic use
Correspondence
Humans
Infections
Male
Pain
Swelling
Toxins
Wound Infection - drug therapy
Wound infections
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Summary:Bacillus cereus is a ubiquitous gram-positive rod found in soil. It is usually nonpathogenic, although serious infections may occur. Serious infections caused by B. cereus are related to toxin production and occur following operative procedures, traumatic wounds, and burns. B. cereus wound infections are felt to be due to secondary contamination of the traumatized area by this organism. Wound and skin infections in patients with and without underlying disease have been reported. Despite the seriousness of these wound infections, mortality remains low. The purulence and necrotic nature of B. cereus wound infections are the result of a hemolysin toxin that is liberated by the organism. This hemolysin toxin is immunologically related to streptolysin O, phospholipases, proteolytic enzymes, penicillinase, and lecithinase.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/16.1.189