Frequency and antimicrobial resistance of Acinetobacter species in a university hospital of Buenos Aires City

• Published in: Revista argentina de microbiología 2014-10, Vol.46 (4), p.320-324
• Main Authors: Rodríguez, Carlos Hernán, Nastro, Marcela, Dabos, Laura, Vay, Carlos, Famiglietti, Angela
• Format: Article
• Language: Spanish
• Subjects: Acinetobacter - drug effects; Acinetobacter - isolation & purification; Anti-Infective Agents - pharmacology; Argentina; Hospitals, University; Humans; Microbial Sensitivity Tests; Prospective Studies; Urban Health
• ISSN: 0325-7541
• DOI: 10.1016/S0325-7541(14)70090-2

Two-hundred Acinetobacter isolates belonging to 200 patients admitted to Hospital de Clínicas José de San Martín during the period March 2013-June 2014 were analyzed. The identification was performed by mass spectrometry and was confirmed by molecular methods. Susceptibility to antimicrobials was studied by the Vitek-2 system. A 94% correlation of both identification methods was found. Multidrug resistant Acinetobacter baumannii was the predominant genomic species (92.6%) in hospital-acquired infections, whereas Acinetobacter pitti and Acinetobacter nosocomialis accounted for 3.5% and 0.5% of the isolates recovered, respectively. In community-acquired infections a major predominance of the different genomic species was observed. Acinetobacter johnsonii and A. baumannii are the most frequent species, accounting for 45.9% of the isolates recovered. Resistance to carbapenems and minocycline was only observed in A. baumannii. Mass spectrophotometry was an effective tool for the identification of the different genomic species.