Serum insulin is significantly related to components of the metabolic syndrome in Japanese working women

Abstract Background The aim of this study was to examine the association between serum insulin levels and components of the metabolic syndrome (MetS) in working women. Methods The target subjects were 141 working women. Serum triglyceride, HDL cholesterol, uric acid, plasma insulin and plasma glucos...

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Published in:Diabetes & metabolic syndrome clinical research & reviews 2011-10, Vol.5 (4), p.188-190
Main Authors: Kawada, Tomoyuki, Otsuka, Toshiaki, Inagaki, Hirofumi, Wakayama, Yoko, Li, Qing, Li, Ying-Ji, Katsumata, Masao
Format: Article
Language:English
Subjects:
Adult
Biomarkers - blood
Blood Glucose - analysis
Blood Pressure
Body Mass Index
Cholesterol, HDL - blood
Cross-Sectional Studies
Endocrinology & Metabolism
Female
Humans
Insulin - blood
Japan - epidemiology
Metabolic syndrome
Metabolic Syndrome - blood
Middle Aged
Prognosis
Risk Factors
Serum insulin
Triglycerides
Waist Circumference
Women, Working
Working women
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Summary:Abstract Background The aim of this study was to examine the association between serum insulin levels and components of the metabolic syndrome (MetS) in working women. Methods The target subjects were 141 working women. Serum triglyceride, HDL cholesterol, uric acid, plasma insulin and plasma glucose were measured in addition to waist circumference and blood pressure. Results MetS was diagnosed based on the modified criteria of the International Diabetes Federation, and was present in 7.1% (10/141) of the study subjects. Stepwise multiple regression analysis showed that some components of MetS were significantly associated with log-transformed values of the serum insulin. The standardized regression coefficient for the waist circumference, high density lipoprotein cholesterol, systolic blood pressure and age were 0.238, −0.333, 0.309 and −0.156, respectively. Conclusions A statistically significant relationship existed between the components of MetS and the serum insulin levels in working women.
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2010.12.005