Comparative efficacy of pure yellow (577-nm) and 810-nm subthreshold micropulse laser photocoagulation combined with yellow (561–577-nm) direct photocoagulation for diabetic macular edema

Purpose To compare the efficacy of 577- and 810-nm subthreshold micropulse laser photocoagulation (SMLP) combined with direct photocoagulation to microaneurysms in diabetic macular edema (DME). Methods A prospective nonrandomized interventional case series. Forty-nine consecutive patients (53 eyes)...

Full description

Saved in:
Bibliographic Details
Published in:Japanese journal of ophthalmology 2015-01, Vol.59 (1), p.21-28
Main Authors: Inagaki, Keiji, Ohkoshi, Kishiko, Ohde, Sachiko, Deshpande, Gautam A., Ebihara, Nobuyuki, Murakami, Akira
Format: Article
Language:English
Subjects:
Aged
Aneurysm - diagnosis
Aneurysm - physiopathology
Aneurysm - surgery
Blood-Retinal Barrier
Capillary Permeability
Clinical Investigation
Diabetic Retinopathy - diagnosis
Diabetic Retinopathy - physiopathology
Diabetic Retinopathy - surgery
Female
Fluorescein Angiography
Humans
Laser Coagulation - instrumentation
Laser Coagulation - methods
Macular Edema - diagnosis
Macular Edema - physiopathology
Macular Edema - surgery
Male
Medicine
Medicine & Public Health
Middle Aged
Ophthalmology
Prospective Studies
Retinal Vessels - pathology
Retinal Vessels - surgery
Tomography, Optical Coherence
Treatment Outcome
Visual Acuity - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To compare the efficacy of 577- and 810-nm subthreshold micropulse laser photocoagulation (SMLP) combined with direct photocoagulation to microaneurysms in diabetic macular edema (DME). Methods A prospective nonrandomized interventional case series. Forty-nine consecutive patients (53 eyes) with DME were recruited. In 20/24 (83.3 %) eyes, 810-nm SMLP (810-nm MP) to achieve a confluent grid pattern was followed by direct photocoagulation to microaneurysms via a continuous 561-nm wavelength laser. In 21/29 (72.5 %) eyes, 577-nm SMLP (577-nm MP) was combined with direct photocoagulation to microaneurysms via the same instrument. Best-corrected visual acuity (BCVA) and central macular thickness (CMT) were examined 1, 2, 3, 6 and 12 months after treatment. Results The mean power required for SMLP was lower in the 577-nm than in the 810-nm MP group (204.1 vs. 954.1 mW) ( p  
ISSN:1613-2246
0021-5155
1613-2246
DOI:10.1007/s10384-014-0361-1