Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat

Highlights • Asenapine (ASE) is a novel atypical antipsychotic designated for treatment of schizophrenia. • ASE effect on Fos expression in striatum, septum, nucleus accumbens, and prefrontal cortex was studied. • ASE induced significant Fos expression almost in all the striatal structures analyzed....

Full description

Saved in:
Bibliographic Details
Published in:Brain research bulletin 2014-09, Vol.108, p.60-66
Main Authors: Majercikova, Zuzana, Cernackova, Alena, Horvathova, Lubica, Osacka, Jana, Pecenak, Jan, Kiss, Alexander
Format: Article
Language:English
Subjects:
Animals
Antipsychotic Agents - pharmacology
Asenapine
Chronic unpredictable variable mild stress (CMS)
Fos expression
Heterocyclic Compounds, 4 or More Rings - pharmacology
Male
Neurology
Neurons - drug effects
Neurons - metabolism
Prosencephalon - drug effects
Prosencephalon - metabolism
Proto-Oncogene Proteins c-fos - metabolism
Rat
Rats
Rats, Wistar
Stress, Psychological - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693
cites cdi_FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693
container_end_page 66
container_issue
container_start_page 60
container_title Brain research bulletin
container_volume 108
creator Majercikova, Zuzana
Cernackova, Alena
Horvathova, Lubica
Osacka, Jana
Pecenak, Jan
Kiss, Alexander
description Highlights • Asenapine (ASE) is a novel atypical antipsychotic designated for treatment of schizophrenia. • ASE effect on Fos expression in striatum, septum, nucleus accumbens, and prefrontal cortex was studied. • ASE induced significant Fos expression almost in all the striatal structures analyzed. • Chronic unpredictable variable mild stress lasting 21 days did not alter the impact of ASE.
doi_str_mv 10.1016/j.brainresbull.2014.08.006
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1647003057</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0361923014001257</els_id><sourcerecordid>1647003057</sourcerecordid><originalsourceid>FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693</originalsourceid><addsrcrecordid>eNqNks1u1TAQhS0EopfCKyCLFZsE_ySOzQIJlRaQKrEA1pZjj8GXxLnYTkXfgwfG4bYVYtWVZc03Z0bnDEIvKGkpoeLVvh2TCTFBHtdpahmhXUtkS4h4gHZUDrxhQzc8RDvCBW0U4-QEPcl5Tyohe_EYnbCeDlT1cod-n3sPtuDFY2PXAthkiOYQIuCSwJQZYi1GfLFkDL8OdWYO9RsiLt8B-yXB311wLmm1Za11vEYHCcclzWbCdokulNqSsYkOz2FyG1tlcBW7q4b47VYzmfIUPfJmyvDs5j1FXy_Ov5x9aC4_vf949vaysZ2QpfHCd5aqsXOcguGcKeY6rtQge2YAmPDCOUmVUWIwihsYrTfSCedBcSkUP0Uvj7qHtPxcIRc9h2xhmkyEZc2aim4ghJN-uAfKlBKcD6Sir4-oTUvOCbw-pDCbdK0p0VuAeq__DVBvAWoidY2nNj-_mbOOM7i71tvEKvDuCEA15ipA0tkGiBZcqH4W7ZZwvzlv_pOxU4jBmukHXEPeL2uK1XpNdWaa6M_bKW2XRDtCKKuG_AGrbswJ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1629963370</pqid></control><display><type>article</type><title>Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat</title><source>ScienceDirect Journals</source><creator>Majercikova, Zuzana ; Cernackova, Alena ; Horvathova, Lubica ; Osacka, Jana ; Pecenak, Jan ; Kiss, Alexander</creator><creatorcontrib>Majercikova, Zuzana ; Cernackova, Alena ; Horvathova, Lubica ; Osacka, Jana ; Pecenak, Jan ; Kiss, Alexander</creatorcontrib><description>Highlights • Asenapine (ASE) is a novel atypical antipsychotic designated for treatment of schizophrenia. • ASE effect on Fos expression in striatum, septum, nucleus accumbens, and prefrontal cortex was studied. • ASE induced significant Fos expression almost in all the striatal structures analyzed. • Chronic unpredictable variable mild stress lasting 21 days did not alter the impact of ASE.</description><identifier>ISSN: 0361-9230</identifier><identifier>EISSN: 1873-2747</identifier><identifier>DOI: 10.1016/j.brainresbull.2014.08.006</identifier><identifier>PMID: 25171958</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Antipsychotic Agents - pharmacology ; Asenapine ; Chronic unpredictable variable mild stress (CMS) ; Fos expression ; Heterocyclic Compounds, 4 or More Rings - pharmacology ; Male ; Neurology ; Neurons - drug effects ; Neurons - metabolism ; Prosencephalon - drug effects ; Prosencephalon - metabolism ; Proto-Oncogene Proteins c-fos - metabolism ; Rat ; Rats ; Rats, Wistar ; Stress, Psychological - metabolism</subject><ispartof>Brain research bulletin, 2014-09, Vol.108, p.60-66</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693</citedby><cites>FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25171958$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Majercikova, Zuzana</creatorcontrib><creatorcontrib>Cernackova, Alena</creatorcontrib><creatorcontrib>Horvathova, Lubica</creatorcontrib><creatorcontrib>Osacka, Jana</creatorcontrib><creatorcontrib>Pecenak, Jan</creatorcontrib><creatorcontrib>Kiss, Alexander</creatorcontrib><title>Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat</title><title>Brain research bulletin</title><addtitle>Brain Res Bull</addtitle><description>Highlights • Asenapine (ASE) is a novel atypical antipsychotic designated for treatment of schizophrenia. • ASE effect on Fos expression in striatum, septum, nucleus accumbens, and prefrontal cortex was studied. • ASE induced significant Fos expression almost in all the striatal structures analyzed. • Chronic unpredictable variable mild stress lasting 21 days did not alter the impact of ASE.</description><subject>Animals</subject><subject>Antipsychotic Agents - pharmacology</subject><subject>Asenapine</subject><subject>Chronic unpredictable variable mild stress (CMS)</subject><subject>Fos expression</subject><subject>Heterocyclic Compounds, 4 or More Rings - pharmacology</subject><subject>Male</subject><subject>Neurology</subject><subject>Neurons - drug effects</subject><subject>Neurons - metabolism</subject><subject>Prosencephalon - drug effects</subject><subject>Prosencephalon - metabolism</subject><subject>Proto-Oncogene Proteins c-fos - metabolism</subject><subject>Rat</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Stress, Psychological - metabolism</subject><issn>0361-9230</issn><issn>1873-2747</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqNks1u1TAQhS0EopfCKyCLFZsE_ySOzQIJlRaQKrEA1pZjj8GXxLnYTkXfgwfG4bYVYtWVZc03Z0bnDEIvKGkpoeLVvh2TCTFBHtdpahmhXUtkS4h4gHZUDrxhQzc8RDvCBW0U4-QEPcl5Tyohe_EYnbCeDlT1cod-n3sPtuDFY2PXAthkiOYQIuCSwJQZYi1GfLFkDL8OdWYO9RsiLt8B-yXB311wLmm1Za11vEYHCcclzWbCdokulNqSsYkOz2FyG1tlcBW7q4b47VYzmfIUPfJmyvDs5j1FXy_Ov5x9aC4_vf949vaysZ2QpfHCd5aqsXOcguGcKeY6rtQge2YAmPDCOUmVUWIwihsYrTfSCedBcSkUP0Uvj7qHtPxcIRc9h2xhmkyEZc2aim4ghJN-uAfKlBKcD6Sir4-oTUvOCbw-pDCbdK0p0VuAeq__DVBvAWoidY2nNj-_mbOOM7i71tvEKvDuCEA15ipA0tkGiBZcqH4W7ZZwvzlv_pOxU4jBmukHXEPeL2uK1XpNdWaa6M_bKW2XRDtCKKuG_AGrbswJ</recordid><startdate>20140901</startdate><enddate>20140901</enddate><creator>Majercikova, Zuzana</creator><creator>Cernackova, Alena</creator><creator>Horvathova, Lubica</creator><creator>Osacka, Jana</creator><creator>Pecenak, Jan</creator><creator>Kiss, Alexander</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20140901</creationdate><title>Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat</title><author>Majercikova, Zuzana ; Cernackova, Alena ; Horvathova, Lubica ; Osacka, Jana ; Pecenak, Jan ; Kiss, Alexander</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>Antipsychotic Agents - pharmacology</topic><topic>Asenapine</topic><topic>Chronic unpredictable variable mild stress (CMS)</topic><topic>Fos expression</topic><topic>Heterocyclic Compounds, 4 or More Rings - pharmacology</topic><topic>Male</topic><topic>Neurology</topic><topic>Neurons - drug effects</topic><topic>Neurons - metabolism</topic><topic>Prosencephalon - drug effects</topic><topic>Prosencephalon - metabolism</topic><topic>Proto-Oncogene Proteins c-fos - metabolism</topic><topic>Rat</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Stress, Psychological - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Majercikova, Zuzana</creatorcontrib><creatorcontrib>Cernackova, Alena</creatorcontrib><creatorcontrib>Horvathova, Lubica</creatorcontrib><creatorcontrib>Osacka, Jana</creatorcontrib><creatorcontrib>Pecenak, Jan</creatorcontrib><creatorcontrib>Kiss, Alexander</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Brain research bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Majercikova, Zuzana</au><au>Cernackova, Alena</au><au>Horvathova, Lubica</au><au>Osacka, Jana</au><au>Pecenak, Jan</au><au>Kiss, Alexander</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat</atitle><jtitle>Brain research bulletin</jtitle><addtitle>Brain Res Bull</addtitle><date>2014-09-01</date><risdate>2014</risdate><volume>108</volume><spage>60</spage><epage>66</epage><pages>60-66</pages><issn>0361-9230</issn><eissn>1873-2747</eissn><abstract>Highlights • Asenapine (ASE) is a novel atypical antipsychotic designated for treatment of schizophrenia. • ASE effect on Fos expression in striatum, septum, nucleus accumbens, and prefrontal cortex was studied. • ASE induced significant Fos expression almost in all the striatal structures analyzed. • Chronic unpredictable variable mild stress lasting 21 days did not alter the impact of ASE.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25171958</pmid><doi>10.1016/j.brainresbull.2014.08.006</doi><tpages>7</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0361-9230
ispartof Brain research bulletin, 2014-09, Vol.108, p.60-66
issn 0361-9230
1873-2747
language eng
recordid cdi_proquest_miscellaneous_1647003057
source ScienceDirect Journals
subjects Animals
Antipsychotic Agents - pharmacology
Asenapine
Chronic unpredictable variable mild stress (CMS)
Fos expression
Heterocyclic Compounds, 4 or More Rings - pharmacology
Male
Neurology
Neurons - drug effects
Neurons - metabolism
Prosencephalon - drug effects
Prosencephalon - metabolism
Proto-Oncogene Proteins c-fos - metabolism
Rat
Rats
Rats, Wistar
Stress, Psychological - metabolism
title Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T13%3A40%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20acute%20asenapine%20treatment%20on%20Fos%20expression%20in%20the%20forebrain%20structures%20under%20normal%20conditions%20and%20mild%20stress%20preconditioning%20in%20the%20rat&rft.jtitle=Brain%20research%20bulletin&rft.au=Majercikova,%20Zuzana&rft.date=2014-09-01&rft.volume=108&rft.spage=60&rft.epage=66&rft.pages=60-66&rft.issn=0361-9230&rft.eissn=1873-2747&rft_id=info:doi/10.1016/j.brainresbull.2014.08.006&rft_dat=%3Cproquest_cross%3E1647003057%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c468t-f6f4c19b4d31ea33292d43997852aee26f6dd819a967a93aebcfa8d6dfe938693%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1629963370&rft_id=info:pmid/25171958&rfr_iscdi=true