Performance of a parallel diagnostic algorithm for HIV diagnosis in low risk pediatric and obstetric patient populations

Highlights • Performance of a WB-independent antibody-based algorithm for HIV testing evaluated. • Evaluations performed in low risk pediatric and obstetric patient populations. • Notable differences seen in the specificities of the various antibody-based assays. • Specificities varied depending on...

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Bibliographic Details
Published in:Journal of clinical virology 2014-11, Vol.61 (3), p.418-422
Main Authors: Chandramohan, Lakshmi, Vargas, German, Dowlin, Michael, Agarwal, Shweta, Buffone, Gregory, Devaraj, Sridevi, Revell, Paula A
Format: Article
Language:English
Subjects:
Adolescent
Algorithms
Allergy and Immunology
Child
Child, Preschool
Diagnostic Tests, Routine - methods
Female
HIV diagnosis
HIV Infections - diagnosis
Human immunodeficiency virus 1
Human immunodeficiency virus 2
Humans
Infant
Infectious Disease
Low risk
Male
Obstetric
Obstetrics - methods
Pediatric
Pediatrics - methods
Sensitivity and Specificity
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Summary:Highlights • Performance of a WB-independent antibody-based algorithm for HIV testing evaluated. • Evaluations performed in low risk pediatric and obstetric patient populations. • Notable differences seen in the specificities of the various antibody-based assays. • Specificities varied depending on the low risk patient population. • Bio-Rad Multispot displayed low specificities in pediatric and obstetric patients.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2014.08.007