Blind Focusing of Electromagnetic Fields in Hyperthermia Exploiting Target Contrast Variations

This paper suggests a novel approach to the blind focusing of the electromagnetic field for microwave hyperthermia. The idea is to induce a contrast variation in the target and to exploit this variation for the synthesis of the excitations of the antenna array employed for the focusing, by performin...

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Bibliographic Details
Published in:IEEE transactions on biomedical engineering 2015-01, Vol.62 (1), p.208-217
Main Authors: Bellizzi, Gennaro, Bucci, Ovidio M.
Format: Article
Language:English
Subjects:
Algorithms
Antenna arrays
Antenna measurements
Antennas
Arrays
Biomedical measurement
Blindness
Blinds
Breast Neoplasms - diagnosis
Breast Neoplasms - physiopathology
Breast Neoplasms - therapy
Diagnosis, Computer-Assisted - methods
Electromagnetic Fields
Excitation
Focusing
Humans
Hyperthermia
Hyperthermia, Induced - methods
Magnetic resonance imaging
Mathematical analysis
Microwaves - therapeutic use
Models, Biological
Nanoparticles - therapeutic use
Scattering
Therapy, Computer-Assisted - methods
Vectors (mathematics)
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Summary:This paper suggests a novel approach to the blind focusing of the electromagnetic field for microwave hyperthermia. The idea is to induce a contrast variation in the target and to exploit this variation for the synthesis of the excitations of the antenna array employed for the focusing, by performing a differential scattering measurement. In particular, the excitation vector is set as the right singular vector associated with the largest singular value of the differential scattering matrix, obtained as difference of two scattering matrixes measured by the antenna array itself before and after the contrast change. As a result, the approach is computationally effective and totally blind, not requiring any a priori knowledge of the electric and geometric features of the region hosting the target, as well as of its spatial position with respect to the antenna array.
ISSN:0018-9294
1558-2531
DOI:10.1109/TBME.2014.2344711