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Secretory phospholipase A sub(2) is the principal bactericide for staphylococci and other gram-positive bacteria in human tears
We examined human tears for molecules that killed gram-positive bacteria. The principal mediator of bactericidal activity against staphylococci proved to be a calcium-dependent enzyme, secretory phospholipase A sub(2). Whereas the concentration of secretory phospholipase A sub(2) in the normal tear...
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Published in: | Infection and immunity 1998-06, Vol.66 (6), p.2791-2797 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Online Access: | Get full text |
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Summary: | We examined human tears for molecules that killed gram-positive bacteria. The principal mediator of bactericidal activity against staphylococci proved to be a calcium-dependent enzyme, secretory phospholipase A sub(2). Whereas the concentration of secretory phospholipase A sub(2) in the normal tear film exceeded 30 mu g/ml, only 1.1 ng ( |
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ISSN: | 0019-9567 |