Miliary Tuberculosis with Paradoxical Expansion of Intracranial Tuberculomas Complicating Human Immunodeficiency Virus Infection in a Patient Receiving Highly Active Antiretroviral Therapy

The paradoxical expansion of tuberculomas during the course of tuberculous chemotherapy has been reported occasionally. To our knowledge, the phenomenon has been reported only once in the context of HIV infection, and in that case it occurred after the patient's therapy had been switched to iso...

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Bibliographic Details
Published in:Clinical infectious diseases 1998-04, Vol.26 (4), p.1008-1009
Main Authors: Crump, John A., Tyrer, Mervyn J., Owen, Simon J. Lloyd, Han, Loong Y., Lipman, Marc C., Johnson, Margaret A.
Format: Article
Language:English
Subjects:
AIDS
Biological and medical sciences
Brief Reports
Chemotherapy
Highly active antiretroviral therapy
HIV
Human viral diseases
Infections
Infectious diseases
Intracranial tuberculoma
Lymph nodes
Medical sciences
Miliary tuberculosis
Tropical medicine
Tuberculoma
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral load
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Summary:The paradoxical expansion of tuberculomas during the course of tuberculous chemotherapy has been reported occasionally. To our knowledge, the phenomenon has been reported only once in the context of HIV infection, and in that case it occurred after the patient's therapy had been switched to isoniazid prophylaxis. We know of no case other than the one we describe in which expansion of tuberculomas occurred concurrently to the induction of highly active antiretroviral therapy (HAART).
ISSN:1058-4838
1537-6591
DOI:10.1086/517636