Synthesis of trifluoromethylated [1,4]diazepines from 1,1,1-trifluoroalk-3-yn-2-ones

Reaction of 1,1,1-trifluoroalk-3-yn-2-ones with 1,2-diamines affords trifluoromethylated [1,4]diazepines.

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Bibliographic Details
Published in:Mendeleev communications 2014-09, Vol.24 (5), p.269-271
Main Authors: Romanov, Alexey R., Rulev, Alexander Yu, Ushakov, Igor A., Muzalevskiy, Vasiliy M., Nenajdenko, Valentine G.
Format: Article
Language:English
Subjects:
Synthesis
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Description
Summary:Reaction of 1,1,1-trifluoroalk-3-yn-2-ones with 1,2-diamines affords trifluoromethylated [1,4]diazepines.
ISSN:0959-9436
DOI:10.1016/j.mencom.2014.09.007