One-dimensional nanostructures based bio-detection

This paper presents a review on recent developments of one-dimensional (1-D) nanostructures based label-free chemiresistive/chemFET biosensors and the various sensing mechanisms used for biomolecular detection. The sensor performance including sensitivity, selectivity, and reliability is compared in...

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Bibliographic Details
Published in:Biosensors & bioelectronics 2015-01, Vol.63, p.432-443
Main Authors: Chartuprayoon, Nicha, Zhang, Miluo, Bosze, Wayne, Choa, Yong-Ho, Myung, Nosang V.
Format: Article
Language:English
Subjects:
Bioaffinity
Bioelectricity
Biological and medical sciences
Biosensing Techniques - methods
Biosensors
Biotechnology
ChemFET
Chemiresistive
Detection
Electrochemical Techniques - methods
Fundamental and applied biological sciences. Psychology
Label-free biosensor
Materials selection
Methods. Procedures. Technologies
Nanostructure
Nanostructures - chemistry
Nanotubes, Carbon - chemistry
Nanowires - chemistry
Sensing mechanism
Sensors
Synthesis
Transistors, Electronic
Various methods and equipments
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Summary:This paper presents a review on recent developments of one-dimensional (1-D) nanostructures based label-free chemiresistive/chemFET biosensors and the various sensing mechanisms used for biomolecular detection. The sensor performance including sensitivity, selectivity, and reliability is compared in terms of material synthesis of the sensor's element, relating surface functionalization schemes to their properties with respect to selected bioreceptors, its method of fabrication, and its intended operation. As a final point, we outline the prospects of chemiresistive/chemFET biosensors and recommend specific advancements in this field. •One-dimensional label-free chemiresistive/chemFET biosensors are reviewed.•Various sensing configuration and mechanisms are studied.•Factors impacting the sensing performance are summarized.•The prospects of chemiresistive/chemFET biosensors are outlined.
ISSN:0956-5663
1873-4235
DOI:10.1016/j.bios.2014.07.043