Quality of life by proxy and mortality in institutionalized older adults with dementia

Aim This study aimed at analyzing the effect of quality of life (QoL) on mortality in older adults with dementia living in long‐term care facilities. Methods A prospective observational cohort study was carried out on 412 residents aged older than 60 years, diagnosed with dementia according to the D...

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Bibliographic Details
Published in:Geriatrics & gerontology international 2015-01, Vol.15 (1), p.38-44
Main Authors: González-Vélez, Abel E, Forjaz, María Joao, Giraldez-García, Carolina, Martín-García, Salomé, Martínez-Martín, Pablo
Format: Article
Language:English
Subjects:
Dementia
Dementia - diagnosis
Dementia - mortality
Dementia - psychology
Female
Follow-Up Studies
Humans
Long-Term Care
long-term care settings
Male
Middle Aged
Mortality
Neuropsychological Tests
older adults
Older people
Prospective Studies
Psychiatric Status Rating Scales
Quality of Life
Spain - epidemiology
Surveys and Questionnaires
Survival Rate - trends
Time Factors
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Summary:Aim This study aimed at analyzing the effect of quality of life (QoL) on mortality in older adults with dementia living in long‐term care facilities. Methods A prospective observational cohort study was carried out on 412 residents aged older than 60 years, diagnosed with dementia according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. Besides assessment of QoL (EQ‐5D index by proxy) and perceived health status (EQ‐VAS), baseline measurements included severity of dementia (Clinical Dementia Rating Scale [CDR]), comorbidity (number of self‐reported chronic conditions), disability evaluation (Barthel Index), cognitive state (Mini Examen Cognoscitivo, a validated and modified Spanish version of the Mini‐Mental State Examination) and depression (Cornell Depression Scale for Dementia). Sociodemographic and clinical variables were analyzed as potential effect modifiers and confounders in the relationship between QoL and mortality using a multivariate logistic regression analysis. Results After an 18‐month follow up, 138 residents had died. Adjusting for CDR and Barthel Index, the odds of mortality were multiplied by 0.25 (95% CI 0.09–0.70) and 0.79 (95% CI 0.26–2.42) for every unit of change in the EQ‐5D index in the residents with Cornell score
ISSN:1444-1586
1447-0594
DOI:10.1111/ggi.12225