No shortcut solution to the problem of Y-STR match probability calculation

Highlights • Haplotype data of 21 Y-STRs (from PPY23) were analyzed in six populations. • Entropy was used as a measure of haplotype diversity. • The seven most rapidly mutating Y-STRs explain >94% of the overall entropy. • No decomposition of PPY23 into sets of independent Y-STRs is feasible. •...

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Bibliographic Details
Published in:Forensic science international : genetics 2015-03, Vol.15, p.69-75
Main Authors: Caliebe, Amke, Jochens, Arne, Willuweit, Sascha, Roewer, Lutz, Krawczak, Michael
Format: Article
Language:English
Subjects:
Chromosomes, Human, Y
Haplotypes
Humans
Microsatellite Repeats - genetics
Pathology
Probability
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Summary:Highlights • Haplotype data of 21 Y-STRs (from PPY23) were analyzed in six populations. • Entropy was used as a measure of haplotype diversity. • The seven most rapidly mutating Y-STRs explain >94% of the overall entropy. • No decomposition of PPY23 into sets of independent Y-STRs is feasible. • Match probabilities cannot be transformed into products of less intricate factors.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2014.10.016